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D-Glutamic Acid
go.drugbank.com/drugs/DB02517ExperimentalGlutamic acid is the most common excitatory neurotransmitter in the central nervous system.
Pamufetinib
go.drugbank.com/drugs/DB20752InvestigationalThe usage of the INN stem '-tinib' in the name indicates that Pamufetinib is a tyrosine kinase inhibitor. Pamufetinib is under investigation in clinical trial NCT04999761 (AB122 Platform Study).
Halofuginone
go.drugbank.com/drugs/DB04866InvestigationalVet approvedFood and Drug Administration in March, 2000. … Halofuginone also effectively suppresses tumor progression and metastasis in mice.
(1H-indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid
go.drugbank.com/drugs/DB03455ExperimentalThese are compounds containing an acetic acid (or a derivative) linked to the C3 carbon atom of an indole. (1H-indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid is known to target interleukin-2.
Gemogenovatucel-T
go.drugbank.com/drugs/DB17412InvestigationalFurin is a convertase involved in the activation of TGFβ-1 and TGFβ-2.[A255163] Gemogenovatucel-T is being investigated in the treatment of various cancers. … Gemogenovatucel-T is a bi-shRNA furin/Granulocyte Macrophage Colony Stimulating Factor (GMCSF) Augmented autologous tumour cell vaccine.
Synonyms: Gemogenovatucel-TSapanisertib
go.drugbank.com/drugs/DB11836InvestigationalSapanisertib has been used in trials studying the treatment of HCC, Solid Tumor, Gliosarcoma, Liver Cancer, and Glioblastoma, among others.
TAK-448
go.drugbank.com/drugs/DB11975InvestigationalTAK-448 has been used in trials studying the treatment of Prostate Cancer, Low Testosterone, Prostatic Neoplasms, and Hypogonadotropic Hypogonadism.
Exatecan
go.drugbank.com/drugs/DB12185InvestigationalExatecan has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Lung Cancer, and Liver Cancer, among others.
Amenamevir
go.drugbank.com/drugs/DB11701InvestigationalAmenamevir has been used in trials studying the treatment of Herpes Zoster, Herpes Simplex, Herpes Genitalis, and Safety of Amenamevir.
AZD-1236
go.drugbank.com/drugs/DB11961InvestigationalAZD1236 has been used in trials studying the basic science and treatment of Cystic Fibrosis and Chronic Obstructive Pulmonary Disease.