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Licofelone
go.drugbank.com/drugs/DB04725ExperimentalIt is currently under evaluation as a treatment for osteoarthritis (OA), the most common form of arthritis. … Developed by the German pharmaceutical company, Merckle GmbH, together with EuroAlliance partners Alfa Wassermann and Lacer, licofelone (ML3000) is a dual COX/LOX inhibitor and the first member of this
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingLumiflavin
go.drugbank.com/drugs/DB04726ExperimentalSynonyms: 7,8,10-Trimethylbenzo(g)pteridine-2,4(3H,10H)-dioneCategories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 3-Ring2-Hydroxyquinoline
go.drugbank.com/drugs/DB04745ExperimentalSynonyms: 2-quinolone, α-QuinoloneCategories: Heterocyclic Compounds, 2-RingPurvalanol A
go.drugbank.com/drugs/DB04751ExperimentalSynonyms: 2-(1R-Isopropyl-2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine, Purvalanol ACategories: Heterocyclic Compounds, 2-RingBithionol
go.drugbank.com/drugs/DB04813ApprovedWithdrawnBithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders.
Synonyms: 2-Hydroxy-3,5-dichlorophenyl sulfide, 2-Hydroxy-3,5-dichlorophenyl sulphideMethapyrilene
go.drugbank.com/drugs/DB04819ApprovedWithdrawnMethapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979.
Synonyms: N-(α-pyridyl)-N-(α-thenyl)-N',N'-dimethylethylenediamine, N,N-dimethyl-N'-pyrid-2-yl-N'-2-thenylethylenediamineCategories: Heterocyclic Compounds, 1-RingNomifensine
go.drugbank.com/drugs/DB04821ApprovedWithdrawnFDA published a notice of its determination that Merital capsules were removed from the market for safety reasons (see the Federal Register of June 17, 1986 (51 FR 21981)).
Synonyms: D,L-nomifensine, 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamineCategories: Heterocyclic Compounds, 2-RingLysergic acid diethylamide
go.drugbank.com/drugs/DB04829IllicitInvestigationalMany emotionally intense experiences can lead to flashbacks when a person is reminded acutely of the original experience. … Some say HPPD is a manifestation of post-traumatic stress disorder, not related to the direct action of LSD on brain chemistry, and varies according to the susceptibility of the individual to the disorder
Synonyms: N,N-diethyl-D-lysergamide, N,N-diethyllysergamideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMepenzolate
go.drugbank.com/drugs/DB04843ApprovedWithdrawnPharmacologically, it is a post-ganglionic parasympathetic inhibitor. … Mepenzolate is a post-ganglionic parasympathetic inhibitor. It decreases gastric acid and pepsin secretion and suppresses spontaneous contractions of the colon.
Categories: Heterocyclic Compounds, 1-Ring