Bithionol

DB04813ApprovedWithdrawnSmall molecule

Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the... Approvals of the NDA's for bithionol drug products were withdrawn on October 24, 1967 (see the Federal Register of October 31, 1967 (32 FR 15046)).

Chemical structure of Bithionol
Formula / weight
C12H6Cl4O2S · 356.052 g/mol (avg)
Also known as
Bithionol sulfide · Bithionolate
Code names
Caswell No. 852 · CP 3438 · USAF B-22

Resolves to

Compound
UNIIAMT77LS62OCAS97-18-7ChEMBLCHEMBL290106ChEBI3131PubChem2406KEGGD00802
Clinical / RWD
ATCD10AB01ATCP02BX01
Structure
InChIKeyJFIOVJDNOJYLKP-UHFFFAOYSA-NSMILESOC1=C(SC2=C(O)C(Cl)=CC(Cl)=C2)C=C(Cl)C=C1Cl
Targets
Q07820MCL1Q92731ESR2P17655CAPN2P03372ESR1

What you can answer from here — as of September 13, 2026

4Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
1Clinical trialPhase, status and sponsor resolved per trial
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2ATC codesIncluding every combination product, plus 13 drug categories
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4+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Bithionol, and which of those have an active Phase 3 trial?

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