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X-376
go.drugbank.com/drugs/DB13104InvestigationalX-376 is an inhibitor of the anaplastic lymphoma kinase (ALK) which can penetrate the blood brain barrier.[A265085]
Synonyms: (R)-6-Amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-N-(4-(4-methylpiperazine-1-carbonyl)phenyl)pyridazine-3-carboxamideCilengitide
go.drugbank.com/drugs/DB11890InvestigationalCilengitide has been used in trials studying the treatment of Sarcoma, Gliomas, Lymphoma, Leukemia, and Lung Cancer, among others.
MK-0893
go.drugbank.com/drugs/DB12044InvestigationalMK0893 has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Diabetes Mellitus, Type 2.
Lenabasum
go.drugbank.com/drugs/DB12193InvestigationalAjulemic acid has been used in trials studying the treatment of Cystic Fibrosis, Dermatomyositis, and Diffuse Cutaneous Systemic Sclerosis.
Labetuzumab govitecan
go.drugbank.com/drugs/DB12331InvestigationalLabetuzumab govitecan has been used in trials studying the treatment of Colon Cancer, Rectal Cancer, and Metastatic Colorectal Cancer.
Rovadicitinib
go.drugbank.com/drugs/DB21747InvestigationalRovadicitinib is under investigation in clinical trials NCT06682169 and NCT06300320 for the treatment of Chronic Graft-versus-host Disease.
Fleroxacin
go.drugbank.com/drugs/DB04576ExperimentalFleroxacin is not an inhibitor of CYP1A2.[A39048]
Psilocybin
go.drugbank.com/drugs/DB11664InvestigationalIn November, 2019, it was granted Breakthrough Therapy status by the FDA.
Aceneuramic acid
go.drugbank.com/drugs/DB11797InvestigationalAceneuramic acid has been used in trials studying the treatment of Distal Myopathy, Nonaka Type, Hereditary Inclusion Body Myopathy, and Distal Myopathy With Rimmed Vacuoles.
PZ-128
go.drugbank.com/drugs/DB11839InvestigationalPZ-128 has been used in trials studying the prevention and treatment of Heart Diseases, Coronary Disease, Arteriosclerosis, Vascular Diseases, and Myocardial Ischemia, among others.