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Bortezomib
go.drugbank.com/drugs/DB00188ApprovedInvestigational[A204083] In May 2003, bortezomib became the first anticancer proteasome inhibitor that was approved by the FDA under the trade name VELCADE. … [A204083] The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and
Products: BOTEMIB 2.5 MG, BOTEMIB 1.0 MGEdetate copper disodium
go.drugbank.com/drugs/DB14599ExperimentalSynonyms: Copper versenate, Copper disodium edetateLevobupivacaine
go.drugbank.com/drugs/DB01002ApprovedInvestigationalWithdrawnLevobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AstraZeneca under the t...
Products: CHIROCAINE 5.0 MG/ML, CHIROCAINE INJECTION 5 mg/mlMedazepam
go.drugbank.com/drugs/DB13437InvestigationalMixtures: TRANKO-BUSKAS 10 MG + 10 MG KAPLI TABLET, 20 ADET, TRANKO-BUSKAS 10 MG + 10 MG KAPLI TABLET, 40 ADETProducts: NOBRAL 10 MG KAPSÜL, 20 ADET, NOBRAL 10 MG KAPSÜL, 250 ADETIpilimumab
go.drugbank.com/drugs/DB06186ApprovedInvestigational[L12126] Ipilimumab was granted FDA approval on 25 March 2011.[L12126]
Categories: Immunoglobulin GProducts: YERVOY 5 mg/ml concentrate for solution for infusion, YERVOY®5 MG /ML SOLUCION INYECTABLE PARA INFUSION INTRAVENOSAFlumazenil
go.drugbank.com/drugs/DB01205ApprovedInvestigationalimidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine receptor complex
Products: ANEXATE INJECTION 0.5 mg/5 ml, LANEXAT® AMPOLLAS 0.5 MG /5 MLSirolimus
go.drugbank.com/drugs/DB00877ApprovedInvestigational[A242372] In November 2000, the drug was recognized by the European Agency as an alternative to calcineurin antagonists for maintenance therapy with corticosteroids. … formulation of sirolimus, marketed as HYFTOR, was approved by the FDA in April 2022: this marks the first topical treatment approved in the US for facial angiofibroma associated with tuberous sclerosis complex
Products: RAPAMUNE 1 MG 100 FILM DRAJE, RAPAMUNE 0.5 MG TABLET ,100 ADETNogapendekin alfa
go.drugbank.com/drugs/DB18740ApprovedInvestigationalNogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combinat...
Synonyms: Il-15n72d:il-15rec-su/fc soluble complex i, Inbakicept nogapendekin alfa fusion complexPentazocine
go.drugbank.com/drugs/DB00652ApprovedVet approvedIt is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
Products: Pentazocine-Fresenius 30 mg/ml injection, Talwin - Liq 30mg/mlAlirocumab
go.drugbank.com/drugs/DB09302ApprovedInvestigationalAlirocumab is a biopharmaceutical that obtained FDA approval in July 2015 as a second line treatment for high cholesterol in adults whose LDL-cholesterol (LDL-C) is not controlled by the combination of diet and statin treatment. It is a ...
Products: PRALUENT 150 MG/ML (SOLUTION FOR INJECTION IN PRE-FILLED PEN), PRALUENT 75 MG/ML (SOLUTION FOR INJECTION IN PRE-FILLED PEN)