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Carmustine
go.drugbank.com/drugs/DB00262ApprovedInvestigational(From Merck Index, 11th ed) … (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985).
Sepetaprost
go.drugbank.com/drugs/DB12043InvestigationalSepetaprost has been used in trials studying the treatment of Open Angle-glaucoma, Ocular Hypertension, and Mild Open Angle-glaucoma (OAG).
Methadone
go.drugbank.com/drugs/DB00333ApprovedInvestigational) receptor, and as an inhibitor of serotonin and norepinephrine uptake. … [A185888,A185891,A185897] Compared with [morphine], the gold standard reference opioid, methadone also acts as an agonist of κ- and σ-opioid receptors, as an antagonist of the N-methyl-D-aspartate (NMDA
Carboprost tromethamine
go.drugbank.com/drugs/DB00429ApprovedInvestigationalA nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy.
Categories: Genito Urinary System and Sex HormonesNuvaxovid
go.drugbank.com/drugs/DB15810ApprovedInvestigational[L42450,L42965] An updated formulation covering the Omicron XBB.1.5 subvariant was approved in October 2023 in the EU[L48897] and in December 2023 in Canada. … [L49111] In the fall of 2024, an updated formulation covering the Omicron JN.1 subvariant was approved for use in Canada and the US.[L51394,L51399]
Polyethylene glycol
go.drugbank.com/drugs/DB09287ApprovedInvestigationalVet approvedPolyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage. … [A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule.
Mixtures: MACROGOL EG, MACROGOL EGTrenibotulinumtoxinE
go.drugbank.com/drugs/DB19082Approved[L64118] It is the first and only rapid-onset, short-duration botulinum neurotoxin serotype E approved in Europe.[L64118] … [L64095,L64118] It is given as an intramuscular injection into the corrugator and procerus muscles, is intended for occasional use, and its potency units are not interchangeable with those of other botulinum
Synonyms: BOTULINUM NEUROTOXIN SEROTYPE E (BONT/E) (EB-001), BONTOXILYSIN-EClonidine
go.drugbank.com/drugs/DB00575ApprovedInvestigationalClonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors.[A180559] This activity is useful for the treatment of hypertension, severe pain, and ADHD.
ISA101b
go.drugbank.com/drugs/DB18694InvestigationalISA101b (peltopepimut-S) is a therapeutic vaccine against the HPV-specific E6/E7 oncoproteins.
Selenomethionine
go.drugbank.com/drugs/DB11142ApprovedInvestigational*In vivo*, selenomethionine plays an essential role in acting as an antioxidant, where it depletes reactive oxygen species (ROS) and aids in the formation and recycling of glutathione, another important … It can be produced from post-structural modifications.
Mixtures: RE FAC-x, Vital-D Rx