Selenomethionine

DB11142ApprovedInvestigationalSmall molecule

Selenomethionine is a naturally occuring amino acid in some plant materials such as cereal grains, soybeans and enriched yeast but it cannot be synthesized from animals or humans. It can... It can be produced from post-structural modifications.

Mechanism: Pharmacologically active on Glutathione peroxidase 3 and Phospholipid hydroperoxide glutathione peroxidase GPX4
Curator reviewed
Formula / weight: C₅H₁₁NO₂Se · 196.11 g/mol (avg)

Resolves to

Compound

UNII964MRK2PELCAS3211-76-5ChEMBLCHEMBL113178ChEBI62621PubChem105024KEGGC05335

Clinical / RWD

RxNorm9644

Structure

InChIKeyRJFAYQIBOAGBLC-BYPYZUCNSA-NSMILESC[Se]CC[C@H](N)C(O)=O

Targets

P22352GPX3P36969GPX4

What you can answer from here — as of July 06, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

1Drug interactionStructured to mechanism, not free text

13Clinical trialsPhase, status and sponsor resolved per trial

10Marketed productsAcross 2 countries and 7 labellers

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Selenomethionine, and which of those have an active Phase 3 trial?

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