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Rivabazumab pegol
go.drugbank.com/drugs/DB17788InvestigationalRivabazumab pegol is being investigated as a treatment of Pseudomonas aeruginosa lung infections in patients with cystic fibrosis.[A259457]
Synonyms: KB001-A (AN ANTI-PCRV PEGYLATED MONOCLONAL ANTIBODY FRAGMENT TO THE TYPE III SECRETION SYSTEM OF PSEUDOMONAS AERUGINOSA)IMT504
go.drugbank.com/drugs/DB17792InvestigationalIMT504, a non-CpG 24-mer oligodeoxynucleotide, is an immunomodulatory oligonucleotide currently being investigated as a rabies vaccine.[A259467]
Adrulipase alfa
go.drugbank.com/drugs/DB15004InvestigationalMS-1819 is under investigation in clinical trial NCT03481803 (A Phase IIa Study With Escalating Dose of MS1819-SD).
Abrilumab
go.drugbank.com/drugs/DB15076InvestigationalAbrilumab is under investigation in clinical trial NCT01290042 (Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 181.).
Acebilustat
go.drugbank.com/drugs/DB15385InvestigationalAcebilustat is under investigation in clinical trial NCT01748838 (Phase 1 Study Assessing the Safety and Tolerability of CTX-4430).
KYV-101
go.drugbank.com/drugs/DB23168InvestigationalKYV-101 is under investigation in clinical trial NCT06152172 (CARTIMMUNE: Study of Patients With Autoimmune Diseases Receiving KYV-101).
Nifekalant
go.drugbank.com/drugs/DB16008InvestigationalNifekalant is under investigation in clinical trial NCT03855826 (Evaluation of the Efficacy and Safety of Nifekalant Hydrochloride (NIF) Injection).
Alaproclate
go.drugbank.com/drugs/DB13233ExperimentalDevelopment was discontinued due to concerns over hepatotoxicity observed in animal studies. … Alaproclate was developed as one of the first selective serotonin reuptake inhibitor (SSRI) antidepressants by Astra AB (now AstraZeneca) in the 1970s.
Telisotuzumab adizutecan
go.drugbank.com/drugs/DB21832InvestigationalTipiracil (LONSURF) Oral Tablets Plus IV Infused Bevacizumab in Adult Participants With c-Met Protein Above Cutoff Level Above Refractory Metastatic Colorectal Cancer). … Telisotuzumab Adizutecan is under investigation in clinical trial NCT06614192 (A Study Assessing Adverse Events and Disease Activity When Comparing Intravenously (IV) Infused ABBV-400 to Trifluridine and
Guanosine tetraphosphate
go.drugbank.com/drugs/DB04022ExperimentalTwo phosphate groups are esterified to the sugar moiety in the 5' position and the other two in the 2' or 3' position.