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Doxecitine
go.drugbank.com/drugs/DB02594ApprovedInvestigationalDoxecitine is a synthetic form of the naturally occurring pyrimidine deoxyribonucleoside deoxycytidine. … It is an essential component of the deoxyribonucleotide pool required for DNA synthesis and repair.
Synonyms: dC, -d-ribofuranosyl)cytosineCalcium Phosphate
go.drugbank.com/drugs/DB11348ApprovedInvestigationalCalcium phosphate is typically available as an over the counter supplement, antacid, or as an added ingredient in some toothpastes [FDA Label] [L851].
Mixtures: PNV Prenatal Vitamin Plus Vitamin A, TONACAL D3Categories: Compounds used in a research, industrial, or household settingTetradecyl hydrogen sulfate (ester)
go.drugbank.com/drugs/DB11328ApprovedAlso noted was an unspecified number of episodes of epidermal necrosis without significant long-term effects and a 30% incidence of post-sclerosis pigmentation that resolved within a few months [L2035] … Sodium tetradecyl sulfate has been widely used since the 1950s, and in 1978 the first successful report of injecting a 1% solution into spider angiomas in 144 patients was made.
Pipamperone
go.drugbank.com/drugs/DB09286InvestigationalPipamperone is a typical antipsychotic of the _butyrophenone_ family used in the treatment of schizophrenia. … Interestingly, when [risperidone] was created, Janssen suggested it was a more potent version of pipamperone.
Categories: Dopamine D2 Receptor Antagonists, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeEstradiol valerate
go.drugbank.com/drugs/DB13956ApprovedInvestigationalVet approveddue to menopause, for the treatment of hypoestrogenism due to hypogonadism, castration or primary ovarian failure, and for the treatment of advanced androgen-dependent carcinoma of the prostate (for palliation … Estradiol Valerate (also known as E2V) is a pro-drug ester of [DB00783], a naturally occurring hormone that circulates endogenously within the human body.
Mixtures: AI PROFAMILIAPromazine
go.drugbank.com/drugs/DB00420ApprovedVet approvedWithdrawnA phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic.
Categories: Dopamine D2 Receptor Antagonists, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeFlibanserin
go.drugbank.com/drugs/DB04908ApprovedInvestigationalin the brain as well as an effect on increasing norepinephrine and dopamine neurotransmitters. … In February of 2018 Flibanserin was approved by Health Canada under the brand name Addyi for a similar indication as approved by the FDA.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeDimethyl sulfoxide
go.drugbank.com/drugs/DB01093ApprovedInvestigationalVet approvedA highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. … Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
Synonyms: S(O)Me2Mixtures: Fungizyl AC, Fungizyl ALDihydroergotamine
go.drugbank.com/drugs/DB00320ApprovedInvestigationalformulated at 75% of the strength of the existing intranasal product. … A 9,10alpha-dihydro derivative of [ergotamine]. Dihydroergotamine is used as an abortive therapy for migraines.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Heterocyclic Compounds with 4 or More RingsLactic acid
go.drugbank.com/drugs/DB04398ApprovedInvestigationalVet approvedIt is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the resulting lactic acid to create a compound having the formula NaC3H5O3. … Lactic acid was one of active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020.[L14120]
Mixtures: Ti-U-lac Lotion, PERI SOLUTION ASynonyms: DL-Milchsäure, DL-Lactic Acid