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Ethanol
go.drugbank.com/drugs/DB00898ApprovedInvestigationalIt is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages. … A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant.
Mixtures: Prosera Soothing Hand Sanitizer, I D Anti Bacterial Alcohol Based Hand DisinfectantCategories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesNadroparin
go.drugbank.com/drugs/DB08813ApprovedInvestigationalWithdrawnNadroparin is a low molecular weight heparin (LMWH) which, when bound to antithrombin III (ATIII), accelerates the inactivation of factor II and factor Xa. … The amplification of the fibrin clotting cascade is stopped once factors Xa and IIa are inactivated. It is derived from porcine sources and has a mean molecular size of 5000 daltons.
Products: FRAXIPARINE 0.3ML INJ 7,500 IC U AXA, FRAXODI 19000 IU AXA/1 ML SC ENJEKTABL SOLUSYON 2 ENJEKTOROmalizumab
go.drugbank.com/drugs/DB00043ApprovedInvestigational[A39518] Omalizumab was first approved in the US in 2003 [A263507] and in Europe in 2005. … [L50482] It is used to treat a range of immune and inflammatory conditions, including allergies, urticaria, and asthma.[A263507]
Categories: Agents to Treat Airway DiseaseProducts: XOLAIR SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 150MG/1.0ML, XOLAIR SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 75MG/0.5MLLosartan
go.drugbank.com/drugs/DB00678ApprovedInvestigationalLosartan is an angiotensin II receptor blocker (ARB) used to treat hypertension. … [L7423] Losartan was granted FDA approval on 14 April 1995.[L7423]
Mixtures: SARAVANTA-D, CONVERTAL D 100Categories: Angiotensin II Type 1 Receptor Blockers, Angiotensin II Type 2 Receptor BlockersPropofol
go.drugbank.com/drugs/DB00818ApprovedInvestigationalVet approvedPropofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries … IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications.
Synonyms: 2,6-bis(1-methylethyl)phenolInternational brands: IV-ProLixisenatide
go.drugbank.com/drugs/DB09265ApprovedInvestigationalLixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes mellitus (T2DM). … It is sold by Sanofi-Aventis under the brand name Adlyxin in the US[L763] and Lyxumia in the EU.[L764] Adlyxin recieved FDA approval July 28, 2016.[L763]
Mixtures: Soliqua SoloStar 100units/mL+33mcg/mL solution for injection in a pre-filled pen, SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 50MCG/MLCategories: Drugs Used in Diabetes, Glucagon-like peptide-1 (GLP-1) analoguesExemestane
go.drugbank.com/drugs/DB00990ApprovedInvestigationalIt irreversibly binds to the active site of the enzyme resulting in permanent inhibition. … Exemestane is an oral steroidal aromatase inhibitor used in the adjuvant treatment of hormonally-responsive (also called hormone-receptor-positive, estrogen-responsive) breast cancer in postmenopausal
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 6-methyleneandrosta-1,4-diene-3,17-dioneSpiramycin
go.drugbank.com/drugs/DB06145ApprovedInvestigationalWithdrawnSpiramycin is a 16-membered ring macrolide discovered in 1952 as a product of Streptomyces ambofaciens that has been available in oral formulations since 1955, and parenteral formulations since 1987. … Spiramycin is a primarily bacteriostatic macrolide antimicrobial agent with activity against Gram-positive cocci and rods, Gram-negative cocci and also Legionellae, mycoplasmas, chlamydiae, some types
Mixtures: Stomorgyl 2 TabletCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 Enzyme InhibitorsPegfilgrastim
go.drugbank.com/drugs/DB00019ApprovedInvestigational[L9974] NIOPEG (pegfilgrastim), a biosimilar of NEULASTA®, was approved by Health Canada in April 2024 for the prevention of febrile neutropenia in patients with non-myeloid malignancies receiving myelosuppressive … [L9746] Although the risk of developing febrile neutropenia is less than 20% in many readily used chemotherapy regimens,[A248855] infections pose risks of hospitalization and mortalities.
Categories: Compounds used in a research, industrial, or household settingSynonyms: 吉新芬, PEG-G-CSFGemcitabine
go.drugbank.com/drugs/DB00441ApprovedInvestigationalIt is approved by the FDA to treat advanced ovarian cancer in combination with [carboplatin], metastatic breast cancer in combination with [paclitaxel], non-small cell lung cancer in combination with [ … [L32950] It is also being investigated in other cancer and tumour types.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein substratesSynonyms: 2'-Deoxy-2',2'-difluorocytidine, 4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one