Search

Displaying results 921 - 930 of 8695 in total
  1. Drug

    Simethicone

    go.drugbank.com/drugs/DB09512
    ApprovedInvestigational

    Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination. It has a favourable safety profile as it is not systemically absorbed. Simethicone has been in ...

    Products: Ovol for Gas 80 Mg Tablet, Ovol for Gas 180 Mg Tablet
  2. Drug

    STM-217

    go.drugbank.com/drugs/DB17358
    Experimental

    Synonyms: Soluble receptor fused to part of an antibody that is designed to block the growth factor activin a
  3. Drug

    Topiramate

    go.drugbank.com/drugs/DB00273
    ApprovedInvestigational

    In 2004, topiramate was approved for the prevention of migraine in adults. … [A188309,L10544,L43478] Since 2012, the extended-release formulation has been approved in combination with [phentermine] for chronic weight management therapy in adults.

    Categories: P-glycoprotein substrates, Cytochrome P-450 CYP3A InducersProducts: Mar-topiramate, Ran-topiramate
  4. Drug

    Racecadotril

    go.drugbank.com/drugs/DB11696
    Investigational

    Racecadotril has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and Acute Gastroenteritis.

    Products: Hidrasec 10 mg Granulat zur Herstellung einer Suspension zum Einnehmen, Hidrasec 30 mg Granulat zur Herstellung einer Suspension zum Einnehmen
  5. Drug

    Risperidone

    go.drugbank.com/drugs/DB00734
    ApprovedInvestigational

    responsible for some of its undesirable effects. … Risperidone binds with a very high affinity to 5-HT2A receptors, approximately 10-20 fold greater than the drug's binding affinity to D2 receptors, and carries lesser activity at several off-targets which may

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: Mar-risperidone, RISPERDAL CONSTA FOR INJECTION 25 mg/vial
  6. Drug

    Anti-CD7 CAR T-cell therapy

    go.drugbank.com/drugs/DB18128
    Experimental

    Synonyms: A chimeric antigen receptor (CAR) immunotherapy directed against the target protein CD7
  7. Drug

    Manganese gluconate

    go.drugbank.com/drugs/DB11141
    Approved

    Manganese gluconate is a manganese salt of gluconic acid with the chemical formula C12H22MnO14 x 2H2O. It is typically obtained by reacting manganese carbonate with gluconic acid in aqueous medium and then crystallizing the product to fo...

    Mixtures: Cal-mag Plus K, Mn and Zn Caplets, Multivitamins and Minerals for Young Men
  8. Drug

    Dostarlimab

    go.drugbank.com/drugs/DB15627
    ApprovedInvestigational

    Dostarlimab is an IgG<sub>4</sub> humanized monoclonal antibody targeted against the human programmed death receptor-1 (PD-1). … [A234379] Agents acting on the PD-1 pathway, such as [nivolumab] and [pembrolizumab], facilitate endogenous immune-mediated anti-tumor activity and may therefore be used to treat a wide variety of cancers

    Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors
  9. Drug

    Ropeginterferon alfa-2b

    go.drugbank.com/drugs/DB15119
    ApprovedInvestigational

    Polycythemia vera (PV) is the most common Philadelphia chromosome-negative myeloproliferative neoplasm (MPN), characterized by increased hematocrit and platelet/leukocyte counts, an increased risk for … [A242000, A242005] [Interferon alfa-2b] has been used for decades to treat PV but requires frequent dosing and is not tolerated by all patients.

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2A6 InhibitorsSynonyms: PEG-P-IFN-alfa-2b, PEG-P-IFN-alpha-2b
  10. Drug

    Palm oil

    go.drugbank.com/drugs/DB14377
    Investigational

    It is not an approved drug.

    Products: Batana For Scalp And Hair