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Sonolisib
go.drugbank.com/drugs/DB12601InvestigationalSonolisib has been used in trials studying the treatment of Glioblastoma, Prostate Cancer, Advanced Solid Tumors, Advanced BRAF-mutant Cancers, and Non Small Cell Lung Cancer (NSCLC), among others.
Trastuzumab botidotin
go.drugbank.com/drugs/DB17413ExperimentalA166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable
Synonyms: Recombinant humanized IgG1 anti-HER2 monoclonal antibody conjugated to Duostatin-5Carbaspirin calcium
go.drugbank.com/drugs/DB13612InvestigationalCategories: Analgesics, Non-Narcotic, Non COX-2 selective NSAIDSCeramide NP
go.drugbank.com/drugs/DB14111InvestigationalCeramide NP is a lipid molecule included in a group of lipid molecules called ceramides. Ceramides are major lipid components in the stratum corneum of the human skin. … Ceramide 3 consists of a phytosphingosine backbone N-acylated with a saturated fatty acid (stearic acid) [A27233]. It is widely used as a moisturizer in various cosmetic and personal products.
Synonyms: N-oleoylphytosphingosine, N-octadecanoylphytosphingosineBecotatug vedotin
go.drugbank.com/drugs/DB17407InvestigationalMRG-003 is a recombinant humanized anti-human epidermal growth factor receptor monoclonal antibody conjugated to monomethyl auristatin E.
Opaviraline
go.drugbank.com/drugs/DB07884ExperimentalCategories: Non-Nucleoside Reverse Transcriptase InhibitorsAMZ002
go.drugbank.com/drugs/DB17017InvestigationalAMZ002 is a sterile injectable hormone developed as a purified synthetic polypeptide alternative to current FDA-approved epileptic seizure treatments.
Xaluritamig
go.drugbank.com/drugs/DB18137InvestigationalXaluritamig is a novel humanized bispecific T cell recruiting antibody cross-reactive to human and nonhuman primate STEAP1 and CD3.
BacTRL-spike
go.drugbank.com/drugs/DB15811InvestigationalAs of June, 2020, the company is pursuing a Phase 1, Randomized, Observer-Blind, Placebo-Controlled Trial (NCT04334980) to test the safety and immunogenicity of the vaccine. … BacTRL-Spike is composed of a bacterial medium with colony-forming-units of live Bifidobacterium longum engineered to deliver synthetic DNA encoding spike protein from SARS-CoV-2 contained by plasmids.
Octopamine
go.drugbank.com/drugs/DB13251ExperimentalOctopamine is structurally similar to norepinephrine. It has been used as a nootropic, and therefore it and all of its enantiomer are prohibited by the World Anti-doping Agency (WADA) as of 2014.