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Eprotirome
go.drugbank.com/drugs/DB05035InvestigationalEprotirome which is a compound with promising properties for treatment of obesity and dyslipidemia.
XL784
go.drugbank.com/drugs/DB04991InvestigationalXL784 is a potent inhibitor of the ADAM-10 metalloprotease enzyme, a target of significant interest because of its important role in blood vessel formation and cell proliferation. … Results of single dose Phase I clinical trials of XL784 administered orally to 96 healthy volunteers have demonstrated that XL784 has attractive safety and pharmacokinetic profiles.
PRGN-3006
go.drugbank.com/drugs/DB17229InvestigationalPRGN-3006 are autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of human HER1T (kill switch) on the cell surface
Synonyms: Autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane bound Interleukin-15, and a truncated form of human HER1t (kill switch) on the cell surfaceNBF-006
go.drugbank.com/drugs/DB21770InvestigationalNBF-006 is under investigation in clinical trial NCT03819387 (A Study of NBF-006 in Non-small Cell Lung, Pancreatic, or Colorectal Cancer). … This drug is a proprietary siRNA-based lyophilized lipid nanoparticle (LNP).[A273775, L52905]
LX201
go.drugbank.com/drugs/DB04943InvestigationalLX201 is a silicone matrix ocular implant that provides sustained release of cyclosporine A (CsA) locally to the eye over the course of one year. … LX201 is implanted subconjunctivally (beneath the transparent membrane covering the white of the eye) in a minimally invasive procedure.
Epitizide
go.drugbank.com/drugs/DB13989ExperimentalEpitizide is an agent, commonly found in combination [triamterene], used to produce diuresis.
INO-4995
go.drugbank.com/drugs/DB17834ExperimentalINO-4995 is an inositol tetrakisphosphate analog being investigated for Cystic Fibrosis.[A259781]
Synonyms: 2-O-butyryl-1-O-octyl-myo-Inositol 3,4,5,6-tetrakisphosphate octakis(propionoxymethyl)esterHMI-204
go.drugbank.com/drugs/DB18338ExperimentalHMI-204 is an adeno-associated virus serotype HSC15 expressing human arylsulfatase A
Heat stable ricin vaccine
go.drugbank.com/drugs/DB18477InvestigationalHeat stable ricin vaccine is an alum-adjuvanted, heat stable recombinant subunit vaccine.
VGB-R04
go.drugbank.com/drugs/DB18615InvestigationalVGB-R04 is an adeno-associated viral vector delivering human FIX Padua gene.