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Baxdrostat
go.drugbank.com/drugs/DB19090ApprovedInvestigationalOn May 18, 2026, baxdrostat was approved by the FDA as a first-in-class aldosterone synthase inhibitor for the treatment of hypertension in combination with other antihypertensive drugs [L56189]. … It targets aldosterone excess, a primary underlying driver of treatment resistance and organ damage in cardiovascular diseases [A275512, A275515].
Synonyms: (+)-(r)-n-(4-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydroisoquinolin-8-yl)propionamide, N-((8r)-5,6,7,8-tetrahydro-4-(1,2,3,4-tetrahydro-1-methyl-2-oxo-6-quinolinyl)-8-isoquinolinyl)propanamideCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesFarglitazar
go.drugbank.com/drugs/DB19311InvestigationalSynonyms: L-TYROSINE, N-(2-BENZOYLPHENYL)-O-(2-(5-METHYL-2-PHENYL-4-OXAZOLYL)ETHYL)-, N-(O-BENZOYLPHENYL)-O-(2-(5-METHYL-2-PHENYL-4-OXAZOLYL)ETHYL)-L-TYROSINECategories: Heterocyclic Compounds, 1-RingZelquistinel
go.drugbank.com/drugs/DB19336InvestigationalZelquistinel is under investigation in clinical trial NCT06547489 (GATE-251 or Placebo for the Reduction of Symptoms of Major Depressive Disorder).
Synonyms: tert-butyl (4S)-2-[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]-3-oxo-2,5-diazaspiro[3.4]octane-5-carboxylateMitomycin A
go.drugbank.com/drugs/DB19369ExperimentalSynonyms: 6-methoxy analog of mitomycin c, Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-6,8a-dimethoxy-5-methyl-, (1as,8s,8ar,8bs)-Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingNITHIAMIDE
go.drugbank.com/drugs/DB19371ApprovedWithdrawnSynonyms: Acetamide, n-(5-nitro-2-thiazolyl)-, N-(5-nitro-2-thiazolyl)acetamideCategories: Heterocyclic Compounds, 1-RingZoxazolamine
go.drugbank.com/drugs/DB19372ApprovedWithdrawnSynonyms: 2-amino-5-chlorobenzoxazole, 5-chloro-2-benzoxazolamineCategories: Heterocyclic Compounds, 2-RingSyrosingopine
go.drugbank.com/drugs/DB19379ApprovedWithdrawnSynonyms: -dimethoxy-3.beta.,20.alpha.-yohimban-16.beta.-carboxylate 4-hydroxy, Yohimban-16-carboxylic acid, 18-((4-((ethoxycarbonyl)oxy)-3,5-dimethoxybenzoyl)oxy)-11,17-dimethoxy-, methyl ester, (3.beta.,16.beta.,17.alpha.,18.beta.,20.alpha.)-Categories: Heterocyclic Compounds, 2-RingMiramistin ion
go.drugbank.com/drugs/DB19386InvestigationalMiramistin ion is under investigation in clinical trial NCT05561816 (Efficacy and Safety of Dioxidin Versus Miramistin in Superficial Pyoderma).
Synonyms: Benzenemethanaminium, n,n-dimethyl-n-(3-((1-oxotetradecyl)amino)propyl)-Calcimycin
go.drugbank.com/drugs/DB19408InvestigationalPrimarily used as a biochemical tool for studying divalent cations in biological systems, Calcimycin also exhibits antibiotic activity against gram-positive bacteria and fungi. … Calcimycin is an ionophore and polyether antibiotic derived from Streptomyces chartreusensis.
Synonyms: 4-benzoxazolecarboxylic acid, 5-(methylamino)-2-(((2r,3r,6s,8s,9r,11r)-3,9,11-trimethyl-8-((1s)-1-methyl-2-oxo-2-(1h-pyrrol-2-yl)ethyl)-1,7-dioxaspiro(5.5)undec-2-yl)methyl)-, 5-(methylamino)-2-(((2r,3r,6s,8s,9r,11r)-3,9,11-trimethyl-8-((1s)-1-methyl-2-oxo-2-(1h-pyrrol-2-yl)ethyl)-1,7-dioxaspiro(5.5)undec-2-yl)methyl)-4-benzoxazolecarboxylic acidCategories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household settingAzadirachtin
go.drugbank.com/drugs/DB19419InvestigationalAzadirachtin is under investigation in clinical trial NCT06617026 (Short-term Outcome of Medical vs. Surgical Management of Chronic Anal Fissure).
Synonyms: Azadirachtin aCategories: Compounds used in a research, industrial, or household setting