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Lumateperone
go.drugbank.com/drugs/DB06077ApprovedInvestigational[A189093] Further, not only is the new antipsychotic selective for dopamine (D2) receptors in the mesolimbic and mesocortical brain regions, but it also has minimal off-target activity. … [A189093] It has a unique receptor binding profile and differs from other antipsychotics in that it modulates glutamate, serotonin and dopamine, which are all neurotransmitters that contribute to the pathophysiology
Categories: Dopamine D2 Receptor AgonistsCandesartan
go.drugbank.com/drugs/DB13919InvestigationalCandesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is available as a prodrug in the form of [candesartan cilexetil].
Mixtures: EUROPRES - D 16 MG / 12.5 MG TABLETA., CANDESARTAN E IDROCLOROTIAZIDE EGCategories: Agents Acting on the Renin-Angiotensin SystemCarvedilol
go.drugbank.com/drugs/DB01136ApprovedInvestigational[A182306] Carvedilol was granted FDA approval on 14 September 1995.[L7889] … [L7889,L7892] The dual action of carvedilol is advantageous in combination therapies as moderate doses of 2 drugs have a decreased incidence of adverse effects compared to high dose monotherapy in the
Categories: Compounds used in a research, industrial, or household settingProducts: CARVEDILOLO EG, Nu-carvedilolCopper
go.drugbank.com/drugs/DB09130ApprovedInvestigationalCopper is commonly used in contraceptive intrauterine devices (IUD) [L801]. … Copper is a transition metal and a trace element in the body. It is important to the function of many enzymes including cytochrome c oxidase, monoamine oxidase and superoxide dismutase [FDA Label].
Mixtures: Calcium With Mg Zn Mn Cu CR Si and Vit. C & D, Coen.q10w.vit.c and E Beta-car.se Cu Zn MnAprotinin
go.drugbank.com/drugs/DB06692ApprovedInvestigationalWithdrawnThe goal of using of aprotinin was subsequently to minimize end-organ damage resulting from hypotension due to blood loss in surgery and to reduce the necessity for blood transfusions during surgery. … Nevertheless, the drug was formally withdrawn worldwide in May of 2008 after studies confirmed that its use enhanced the risk of complications or death.
Mixtures: SAN. VE TİC. LTD., TISSEEL FIBRIN SEALANT VH S/D (FROZEN)Escitalopram
go.drugbank.com/drugs/DB01175ApprovedInvestigational[A185420] It is used to restore serotonergic function in the treatment of depression and anxiety. … vast majority of citalopram’s clinical activity, with some evidence suggesting that the R-enantiomer of racemic citalopram actively dampens the activity of escitalopram rather than existing simply as an
Products: ESCITALOPRAM EG, ESCITALOPRAM EG STADA ITALIAVamorolone
go.drugbank.com/drugs/DB15114ApprovedInvestigational[L48671,L48676] In December 2023, it was approved in the EU for the treatment of patients ≥4 years of age.[L49505] … [L48676] Vamorolone was approved by the FDA in October 2023 for the management of DMD in patients ≥2 years of age.
Polihexanide
go.drugbank.com/drugs/DB12277ApprovedInvestigational[A1351,A273908] Polihexanide is approved in Europe under the name Akantior for the treatment of _Acanthamoeba_ keratitis, an ocular infection caused by the _Acanthamoeba_ parasite. … [L53003] It was initially approved in August of 2024, and is the first and only approved therapy to treat patients with _Acanthamoeba_ keratitis. [L53143]
Categories: Compounds used in a research, industrial, or household settingLopinavir
go.drugbank.com/drugs/DB01601ApprovedInvestigational[A191757] Lopinavir was previously under investigation in combination with ritonavir for the treatment of COVID-19 caused by SARS-CoV-2.[L12012] … [L11163] Lopinavir is marketed and administered exclusively in combination with [ritonavir] - this combination, first marketed by Abbott under the brand name Kaletra in 2000, is necessary due to lopinavir's
Mixtures: LOPIMUNE ® + RITONAVIR 10 MG - PELLETS EN CÁPSULAS ORALES, LOPINAVIR E RITONAVIR MYLANCategories: Antivirals used in combination for the treatment of HIV infectionsManganese cation
go.drugbank.com/drugs/DB06757ApprovedInvestigationalNutraceutical[L50667] Apart from its use in human health, has been used in the mining industry, welding, smelting, and the manufacture of batteries.[A263657] … [A263657] Manganese can be found in over-the-counter nutritional supplements and vitamins.[A263667] It is commonly used in total parenteral nutrition (TPN) therapy.
Mixtures: Calcium With Mg Zn Mn Cu CR Si and Vit. C & D, Coen.q10w.vit.c and E Beta-car.se Cu Zn MnProducts: Micro Mn