Search
Spevatamig
go.drugbank.com/drugs/DB18471InvestigationalPT886 is a bispecific antibody against Claudin 18.2 and cluster of differentiation 47 (CD47)
Timdarpacept
go.drugbank.com/drugs/DB17544Investigational[A257261] IMM01 is under investigation in clinical trial NCT05140811 (A Study of IMM01 Combined With Azacitidine in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome). … IMM01 is a recombinant human signal regulatory protein α (SIRPα) IgG 1 fusion protein.
Ginkgolide A
go.drugbank.com/drugs/DB06743ExperimentalNutraceuticalGinkgolide A is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inflammatory and immunological disorders.
Resomelagon
go.drugbank.com/drugs/DB21579InvestigationalResomelagon is under investigation in clinical trial NCT06917001 (Clinical Trial Evaluating Safety and Efficacy of Resomelagon on Dengue Infection (RESOVIR-2)). … Resomelagon is a small molecule drug. The usage of the INN stem '-melagon' in the name indicates that Resomelagon is a non-peptidic melanocortin receptor agonist.
Maridebart Cafraglutide
go.drugbank.com/drugs/DB19339InvestigationalMaridebart Cafraglutide is under investigation in clinical trial NCT05669599 (Dose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of AMG 133 in Adult Subjects With Overweight or Obesity
Synonyms: insulinotropic polypeptide receptor) [275-cysteine,295-cysteine,300-glycine,305-cysteine] (human γ1-chain), disulfide with human κ-chain, dimer, 275,275′-bis(thioether) with 7-37-glucagon-like peptide IOxfenicine
go.drugbank.com/drugs/DB04291ExperimentalOxfenicine in an inhibitor of myocardial metabolism of nonesterified fatty acids (NEFA).
Categories: Amino Acids, Peptides, and ProteinsADP/ATP translocase 1
go.drugbank.com/bio_entities/BE0000599TargetHumansIn addition to its ADP:ATP antiporter activity, also involved in mitochondrial uncoupling and mitochondrial permeability transition pore (mPTP) activity (PubMed:31883789). … Proton transporter activity requires free fatty acids as cofactor, but does not transport it (By similarity).
Synonyms: ANT 1LY-3023414
go.drugbank.com/drugs/DB12167InvestigationalLY3023414 has been used in trials studying the treatment of Neoplasm, Solid Tumor, COLON CANCER, BREAST CANCER, and Advanced Cancer, among others.
CUDC-101
go.drugbank.com/drugs/DB12174InvestigationalCUDC-101 has been used in trials studying the treatment of Cancer, Tumors, Liver Cancer, Breast Cancer, and Gastric Cancer, among others.