LY-3023414

DB12167InvestigationalSmall molecule

LY3023414 has been used in trials studying the treatment of Neoplasm, Solid Tumor, COLON CANCER, BREAST CANCER, and Advanced Cancer, among others.

Chemical structure of LY-3023414
Mechanism
Curator reviewed
Formula / weight
C23H26N4O3 · 406.486 g/mol (avg)
Also known as
Samotolisib
Code names
LY-3023414

Resolves to

Compound
UNIIC88817F47YCAS1386874-06-1ChEMBLCHEMBL4297181PubChem57519748
Structure
InChIKeyACCFLVVUVBJNGT-AWEZNQCLSA-NSMILESCO[C@@H](C)CN1C(=O)N(C)C2=C1C1=CC(=CC=C1N=C2)C1=CC(=CN=C1)C(C)(C)O
Targets
P42345MTORP42336PIK3CA

What you can answer from here — as of June 15, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
16Clinical trialsPhase, status and sponsor resolved per trial
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3+ReferencesStructured and connected to the statements they support
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Which drugs share a target with LY-3023414, and which of those have an active Phase 3 trial?

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