Search

Displaying results 9451 - 9460 of 10000 in total
  1. Drug

    Olenasufligene relduparvovec

    go.drugbank.com/drugs/DB16264
    Investigational

    It is an adeno-associated virus (AAV) vector that delivers a functional copy of the human SGSH gene.[L46671]

    Synonyms: Dna (recombinant adeno-associated virus 2 vector lys-saf302 human n-sulfoglucosamine sulfohydrolase cdna-specifying)
  2. Drug

    Olodanrigan

    go.drugbank.com/drugs/DB16266
    Investigational

    Olodanrigan is under investigation in clinical trial NCT03297294 (Safety and Efficacy of EMA401 in Patients With Painful Diabetic Neuropathy (PDN)).

    Categories: Heterocyclic Compounds, 2-Ring
  3. Drug

    Olutasidenib

    go.drugbank.com/drugs/DB16267
    ApprovedInvestigational

    hydroxyglutarate (2-HG), a metabolite that participates in tumerogenesis. … Olutasidenib (FT-2102) is a selective and potent isocitrate dehydrogenase-1 (IDH1) inhibitor approved by the FDA in December 2022.

    Categories: MATE 1 Inhibitors, MATE 2 InhibitorsSynonyms: (s)-5-((1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)amino)-1-methyl-6-oxo-1,6-dihydropyridine-2-carbonitrile, 2-pyridinecarbonitrile, 5-(((1s)-1-(6-chloro-1,2-dihydro-2-oxo-3-quinolinyl)ethyl)amino)-1,6-dihydro-1-methyl-6-oxo-
  4. Drug

    Ontuxizumab

    go.drugbank.com/drugs/DB16270
    Investigational

    Ontuxizumab is a humanized monoclonal antibody that targets endosialin or tumour endothelial marker 1 (TEM-1).

  5. Drug

    Pecavaptan

    go.drugbank.com/drugs/DB16279
    Investigational

    Pecavaptan is under investigation in clinical trial NCT03901729 (A Trial to Study BAY1753011 in Patients With Congestive Heart Failure).

  6. Drug

    Pexmetinib

    go.drugbank.com/drugs/DB16294
    Investigational

    Pexmetinib is under investigation in clinical trial NCT04074967 (Study of ARRY-614 Plus Either Nivolumab or Ipilimumab).

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  7. Drug

    IPI-549

    go.drugbank.com/drugs/DB16296
    Investigational

    IPI-549 is under investigation in clinical trial NCT03795610 (Window of Opportunity Study of IPI-549 in Patients With Locally Advanced HPV+ and HPV- Head and Neck Squamous Cell Carcinoma).

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  8. Drug

    Praliciguat

    go.drugbank.com/drugs/DB16300
    Investigational

    Praliciguat is under investigation in clinical trial NCT03254485 (A Study of the Effect of IW-1973 on the Exercise Capacity of Patients With Heart Failure With Preserved Ejection Fraction (Hfpef)).

    Categories: Guanylyl Cyclase C Agonists, Heterocyclic Compounds, 1-Ring
  9. Drug

    Rocakinogene sifuplasmid

    go.drugbank.com/drugs/DB16316
    Investigational

    Rocakinogene sifuplasmid is under investigation in clinical trial NCT03491683 (INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-diagnosed Glioblastoma

  10. Drug

    GSK-2981278

    go.drugbank.com/drugs/DB16319
    Investigational

    GSK-2981278 is under investigation in clinical trial NCT03004846 (A Study of GSK2981278 Ointment in Subjects With Plaque Psoriasis).

    Categories: Heterocyclic Compounds, 1-RingSynonyms: Ror gama modulator 1