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Displaying results 941 - 950 of 2815 in total
  1. Drug

    Tepotinib

    go.drugbank.com/drugs/DB15133
    ApprovedInvestigational

    approved in Japan in March 2020 for the treatment of non-small cell lung cancers (NSCLC) with _MET_ alterations, and was subsequently granted accelerated approval by the US FDA in February 2021, under the brand

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  2. Drug

    Darolutamide

    go.drugbank.com/drugs/DB12941
    ApprovedInvestigational

    Darolutamide is a nonsteroidal androgen receptor antagonist for the treatment of castrate-resistant, non-metastatic prostate cancer (nmCRPC). This condition occurs in the majority of patients with advanced prostate cancer who have been t...

    Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  3. Drug

    PF-03654764

    go.drugbank.com/drugs/DB12360
    Investigational

    PF-03654764 has been used in trials studying the basic science and treatment of Allergic Rhinitis.

  4. Drug

    Sodium phosphate, monobasic

    go.drugbank.com/drugs/DB09449
    ApprovedInvestigational

    Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.

    Mixtures: CPD/ADSOL Red Cell Preservation Solution System (PL 2209), CPD/ADSOL Red Cell Preservation Solution System (PL 2209)
  5. Drug

    Abametapir

    go.drugbank.com/drugs/DB11932
    Approved

    [A216178] Abametapir was first approved for use in the United States under the brand name Xeglyze on July 27, 2020.[L15163]

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inhibitors
  6. Drug

    Pesampator

    go.drugbank.com/drugs/DB11843
    Investigational

    PF-04958242 has been used in trials studying the basic science and treatment of Schizophrenia and Hearing Loss, Sensorineural.

  7. Drug

    Methscopolamine

    go.drugbank.com/drugs/DB11315
    Approved

    Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The oral tablets...

    Mixtures: Dallergy PE, Allergy DN PE
  8. Drug

    Olmutinib

    go.drugbank.com/drugs/DB13164
    Investigational

    It is available under the brand name Olita made by Hanmi Pharmaceuticals [A19196]. Olmutinib was developed by Hanmi Pharmaceuticals and Boehringer Ingelheim.

  9. Drug

    Prednisolone sodium metazoate

    go.drugbank.com/drugs/DB05340
    Investigational

    ATL-2502(Colal-Pred) is an old drug (prednisolone metasulphobenzoate, a steroid) with a new delivery system that releases the medication only in the colon. Releasing the drug directly into the colon reduces the potential for significant ...

  10. Drug

    GYM329

    go.drugbank.com/drugs/DB18590
    Investigational

    GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH-dependent manner

    Synonyms: recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH dependent manner