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Risankizumab
go.drugbank.com/drugs/DB14762ApprovedInvestigational[L39885] It gained its first global approval in Japan in March 2019, followed by approval in Canada, the US, and Europe in April 2019. … [A254716] Risankizumab is used to treat plaque psoriasis, psoriatic arthritis, and Crohn's disease.[L39885,L44191,L44231] Risankizumab is being investigated for atopic dermatitis.[A254716]
Categories: Amino Acids, Peptides, and Proteins, Skin and Mucous Membrane AgentsProducts: SKYRIZI SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 75MG/0.83ML, SKYRIZI SOLUTION FOR INJECTION IN PRE-FILLED PEN 150MG/MLMetolazone
go.drugbank.com/drugs/DB00524ApprovedInvestigationalIt also tends to lower blood pressure and increase potassium loss.
Categories: Genito Urinary System and Sex Hormones, metolazone and potassium-sparing agentsProducts: Zaroxolyn Tab 10mgZolmitriptan
go.drugbank.com/drugs/DB00315ApprovedInvestigational[A462, L12978] [Sumatriptan] was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. … It is currently available in both tablet and nasal spray forms.[L12978]
Categories: Serotonin-1b and Serotonin-1d Receptor AgonistProducts: ZOMIG 2.5MG, ZOLMITRIPTAN AL 2.5MGMizolastine
go.drugbank.com/drugs/DB12523ApprovedMizolastine is under investigation in clinical trial NCT01928316 (A Bioequivalence Study of Domestic (Made in China) and Imported Mizolastine Tablets in Healthy Volunteers).
Products: MIZOLLEN 10MG, MIZOLLEN 10MG FILMTABLEtilefrine
go.drugbank.com/drugs/DB08985ApprovedWithdrawnEtilefrine is an adrenergic agonist that appears to interact with beta-1 and some alpha-adrenergic receptors. It has been used as a vasoconstrictor agent.
Categories: Adrenergic and Dopaminergic AgentsProducts: ETILEFRINA CLORHIDRATO 10MG/ML. SOLUCION INYECTABLE., ETILEFRINA CLORHIDRATO 10MG/ MLSOLUCIÓN INYECTABLE.Levofloxacin
go.drugbank.com/drugs/DB01137ApprovedInvestigational[A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and several South American countries soon after.[A190663] … [A190663] It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin[A190663] and remains stereochemically stable following administration
Categories: Alimentary Tract and Metabolism, levofloxacin and ornidazoleSynonyms: Ofloxacin S-(-)-formSkin and subcutaneous tissue infections and infestations
go.drugbank.com/conditions/DBCOND0027759Drugs: Amoxicillin · Ceftazidime · Cephalexin · Clavulanic acid · Erythromycin · Metronidazole +3 moreSynonyms: Skin and subcutaneous tissue infections and infestations, Skin and skin-structure infectionThioproperazine
go.drugbank.com/drugs/DB01622ApprovedIt is virtually without antiserotonin and hypotensive action and has no antihistaminic property. … Thioproperazine has a marked cataleptic and antiapomorphine activity associated with relatively slight sedative, hypothermic and spasmolytic effects.
Products: Majeptil Tab 10mgAlendronic acid
go.drugbank.com/drugs/DB00630ApprovedInvestigationalAlendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. … It functions by preventing resorption of bone[FDA Label][A959].
Mixtures: OSTEOCAL 12MG/1000MG/880IU EFERVESAN TABLET, 28 ADET, 70mg/5600IU TabletCategories: alendronic acid and colecalciferol, alendronic acid and alfacalcidol, sequentialAbiraterone
go.drugbank.com/drugs/DB05812ApprovedInvestigational[A3811, A260880, L40968] Abiraterone was first approved by the FDA and EMA on April,[A260880] July,[L47745] and September 2011,[A260880] respectively. … [L54773,L54768] As abiraterone has poor oral bioavailability and is susceptible to hydrolysis by esterases, abiraterone acetate was developed as an orally bioavailable prodrug with enhanced stability
Categories: niraparib and abiraterone, abiraterone and corticosteroidsProducts: Xbira 250mg (Abiraterone Acetate Tablets USP 250mg), ZYTIGA 250mg tablet