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Terbutaline
go.drugbank.com/drugs/DB00871ApprovedInvestigationalTerbutaline was first synthesized in 1966[A230333] and described in the literature in the late 1960s and early 1970s. … [A230328] It is a selective beta-2 adrenergic agonist used as a bronchodilator in asthmatic patients.[A230333,L32093,L32098] Terbutaline was granted FDA approval on 25 March 1974.[L32088]
Mixtures: BRICANYL EXProducts: บรองโคนิล (N)Perflutren
go.drugbank.com/drugs/DB00556ApprovedInvestigationalThe difference in density between the gas-filled bubbles and the blood around them creates an increased level of contrast visible in the resulting ultrasound image. … During echocardiography, activated Perflutren enhances images of the inner edges or borders of the heart, producing an improved image that may enable physicians to better diagnose patients.
Categories: Compounds used in a research, industrial, or household settingAfamelanotide
go.drugbank.com/drugs/DB04931Approved[L9092] Despite its relatively recent approval, afamelanotide has been available for use as an orphan drug in both the US and EU since 2008.[L9122,L9125] … [A187202,A187205] Afamelanotide is currently the only approved drug therapy used in the management of erythropoietic protoporphyria, having received approval in the EU in December 2014[L9119] and subsequent
Categories: Compounds used in a research, industrial, or household settingDobutamine
go.drugbank.com/drugs/DB00841ApprovedInvestigationalA beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.
Synonyms: 3,4-dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-β-phenylethylamineMixtures: Dobutamine Hydrochloride in DextrosePafolacianine
go.drugbank.com/drugs/DB15413ApprovedInvestigational[A242572] On November 29, 2021, the FDA approved pafolacianine as an adjunct imaging agent for intraoperative identification of malignant lesions in adult patients with ovarian cancer. … Pafolacianine targets the folate receptor alpha (FRα) which is upregulated in numerous epithelial malignancies.
Categories: Compounds used in a research, industrial, or household settingEteplirsen
go.drugbank.com/drugs/DB06014ApprovedInvestigational[A244930] It is caused by loss-of-function mutations in the DMD gene coding for dystrophin, an essential protein involved in maintaining the structural integrity and function of muscle fibres. … Eteplirsen was first approved by the FDA in September 2016 for the treatment of Duchenne muscular dystrophy (DMD) in patients with a confirmed mutation of the DMD gene, which codes for dystrophin, that
Synonyms: N-dimethylphosphonamidate) RNA, dimethylamino)](2',3'-dideoxy-2',3'-imino-2',3'-seco)(2'a→5')(C-m5U-C-C-A-A-C-A-m5U-C-A-A-G-G-A-A-G-A-m5U-G-G-C-A-m5U-m5U-m5U-C-m5U-A-G),5'-(P-(4-((2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)carbonyl)-1-piperazinyl)-N,Categories: Compounds used in a research, industrial, or household settingSpinosad
go.drugbank.com/drugs/DB08823ApprovedVet approvedSpinosad is an insecticide based on a compound found in S. spinosa, a bacterial species. … Spinosad is a pediculicide mixture of spinosyn A and spinosyn D (in an approximately 5:1 ratio, respectively) used in the topical treatment of head lice in children (four years old and older) and in adults
Categories: Compounds used in a research, industrial, or household settingGallium Ga-68 gozetotide
go.drugbank.com/drugs/DB16019ApprovedInvestigationalpositive lesions in men with prostate cancer. … [L43542] In December of the same year, the drug was fully authorized by the EMA.[L44682] In Octer 2022, Ga-68 PSMA-11 was approved by Health Canada for diagnostic use in men with prostate cancer.
Categories: Compounds used in a research, industrial, or household settingUbidecarenone
go.drugbank.com/drugs/DB09270ApprovedInvestigationalNutraceutical[A31413] The ubidecarenone is the coenzyme destined for mitochondrial enzyme complexes involved in oxidative phosphorylation in the production of ATP. … [A7874] It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative phosphorylation.
Mixtures: Coen.q10w.vit.c and E Beta-car.se Cu Zn Mn, Nova Q10+E softgelVarenicline
go.drugbank.com/drugs/DB01273ApprovedInvestigationalIn addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full agonism was displayed on alpha7-receptors. On March 9, 2015, the U.S. … Pfizer is conducting an additional safety study of the drug, results of which are expected in late 2015.
Categories: Drugs Used in Addictive Disorders, Drugs Used in Nicotine Dependence