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Displaying results 951 - 960 of 10000 in total
  1. Drug

    Risdiplam

    go.drugbank.com/drugs/DB15305
    ApprovedInvestigational

    [L15331,L15336] Set to be substantially cheaper than other available SMA therapies,[L15351] risdiplam appears to provide a novel and relatively accessible treatment option for patients with SMA regardless … This mechanism of action is similar to its predecessor [nusinersen], the biggest difference being their route of administration: nusinersen requires intrathecal administration, as does the one-time gene

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesProducts: Evrysdi 0,75 mg/mL Oral Çözelti Hazırlamak İçin Toz, 80 ML, Evrysdi Powder for oral solution 0.75 mg/mL
  2. Drug

    Raltegravir

    go.drugbank.com/drugs/DB06817
    ApprovedInvestigational

    Raltegravir is an antiretroviral drug produced by Merck & Co., used to treat HIV infection. It received approval by the U.S. … Food and Drug Administration (FDA) on 12 October 2007, the first of a new class of HIV drugs, the integrase inhibitors, to receive such approval.

    Products: Chewable Tablet 100 mg, ISENTRESS 400 MG FILM KAPLI TABLET, 60 ADET
  3. Drug

    Loperamide

    go.drugbank.com/drugs/DB00836
    ApprovedInvestigational

    [A251610] It is a highly lipophilic synthetic phenylpiperidine opioid that works by binding to mu-opioid receptors on intestinal muscles to decrease intestinal motility and electrolyte loss. … [A251610] Loperamide has a chemical structure that is similar to diphenoxylate and haloperidol;[A6249] however, loperamide works on mu (μ)-opioid receptors to mediate its pharmacological actions.

    Mixtures: Dg Health Anti Diarrheal Anti Gas, Meds on the GoCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Substrates
  4. Drug

    Propafenone

    go.drugbank.com/drugs/DB01182
    ApprovedInvestigational

    An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. The drug is generally well tolerated.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: RYTMONORM 150 MG, RYTMONORM TABLET 150 mg
  5. Drug

    Diflunisal

    go.drugbank.com/drugs/DB00861
    Approved

    Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs. … Diflunisal is used to relieve pain accompanied with inflammation and in the symptomatic treatment of rheumatoid arthritis and osteoarthritis.

    Synonyms: 5-(2,4-difluorophenyl)salicylic acid, 2-(hydroxy)-5-(2,4-difluorophenyl)benzoic acidProducts: Diflimax 500 mg Film Kaplı Tablet (10 adet), DOLPHIN 500 MG FILM KAPLI TABLET, 10 TABLET
  6. Drug

    Antithymocyte immunoglobulin (rabbit)

    go.drugbank.com/drugs/DB00098
    ApprovedInvestigational

    Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of T-cells.

    Synonyms: Lapine T-lymphocyte immune globulin, Anti-T-lymphocyte immune globulin, rabbitCategories: Immunoglobulin G, Increased T Lymphocyte Destruction
  7. Drug

    Somapacitan

    go.drugbank.com/drugs/DB15093
    ApprovedInvestigational

    Somapacitan, also known as NNC0195-0092,[A219136] is a growth hormone analog indicated to treat adults with growth hormone deficiency. … [A219126,L15661] This human growth hormone analog differs by the creation of an albumin binding site, and prolonging the effect so that it requires weekly dosing rather than daily.

    Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersProducts: Sogroya® 10 mg/1.5 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem (1 adet), Sogroya® 5 mg/1.5 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem (1 adet)
  8. Drug

    Neomycin

    go.drugbank.com/drugs/DB00994
    ApprovedInvestigationalVet approved

    [A175042] Neomycin is active against both gram-positive and gram-negative organisms and mediates its pharmacological action by binding to bacterial ribosomes and inhibiting protein synthesis, which is … [L10716] Neomycin is also available in over-the-counter topical products to prevent minor skin infections.

    Mixtures: 10 Person ANSI, THIOCILLINE 500 IU/G + 5 MG/G GÖZ MERHEMİ, 5 GRProducts: TP-NEOCIN 500 WSP NEOMYCIN SULPHATE 500MG/G POWDER, Neomycin 528.5 mg/g Water Soluble Powder
  9. Drug

    Beroctocog alfa

    go.drugbank.com/drugs/DB14473
    ApprovedInvestigational

    Mixtures: ALPHANATE FOR INJECTION 500 iu/vial, ALPHANATE FOR INJECTION 1000 iu/vialProducts: KOATE-DVI 1000 IU/10 ML IV ENJEKSİYON İÇİN LİYOFİLZE TOZ İÇEREN FLAKON, KOATE-DVI 500 IU/5 ML IV ENJEKSİYON İÇİN LİYOFİLZE TOZ İÇEREN FLAKON
  10. Drug

    Ergotamine

    go.drugbank.com/drugs/DB00696
    Approved

    A vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders.

    Synonyms: (5'α)-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotoman-3',6',18-trione, 12'-hydroxy-2'-methyl-5'α-(phenylmethyl)ergotaman-3',6',18-trioneMixtures: CAFERGOT 1 MG/100 MG TABLET, 30 ADET, ERGOTAMINA/CAFEINA 1/100 MG