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Displaying results 9611 - 9620 of 10000 in total
  1. Drug

    Pegcrisantaspase

    go.drugbank.com/drugs/DB16281
    Investigational

    Following Hypersensitivity to Pegaspargase (Oncaspar)). … Pegcrisantaspase is under investigation in clinical trial NCT02257684 (A Dose Confirmation and Pharmacokinetic Study of Pegcrisantaspase Administered as Intravenous (IV) Infusion in Children and Young

    Synonyms: mPEG-R-Crisantaspase, Pegylated dickeya chrysanthemi l-asparaginase
  2. Drug

    Bufotenine

    go.drugbank.com/drugs/DB01445
    ExperimentalIllicit

    A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics. … Bufotenin has been used as a tool in CNS studies and misused as a psychedelic.

    Categories: N,N-Dimethyltryptamine, Heterocyclic Compounds, 2-RingSynonyms: 3-[2-(dimethylamino)ethyl]-5-indolol, 3-[2-(dimethylamino)ethyl]indol-5-ol
  3. Drug

    Acloproxalap

    go.drugbank.com/drugs/DB21553
    Investigational

    Acloproxalap is under investigation in clinical trial NCT06685692 (A Clinical Trial Investigating the Safety and Efficacy of Subjects With Alcohol Associated Hepatitis (Part 1)). … Acloproxalap is a small molecule drug.

    Categories: Heterocyclic Compounds, 2-Ring
  4. Drug

    Ontuxizumab

    go.drugbank.com/drugs/DB16270
    Investigational

    Ontuxizumab is a humanized monoclonal antibody that targets endosialin or tumour endothelial marker 1 (TEM-1). … It is under investigation in clinical trial NCT01574716 (Sarcoma Study of Morab-004 Utilization: Research and Clinical Evaluation).

  5. Drug

    Mevidalen

    go.drugbank.com/drugs/DB19034
    Investigational

    Mevidalen is under investigation in clinical trial NCT03305809 (A Study of LY3154207 in Participants With Dementia Due to Lewy Body Dementia (LBD) Associated With Idiopathic Parkinson's Disease (PD) or

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 2-(2,6-dichlorophenyl)-1-((1s,3r)-3-(hydroxymethyl)-5-(3-hydroxy-3-methylbutyl)-1-methyl-3,4-dihydroisoquinolin-2(1h)-yl)ethanone, Ethanone, 2-(2,6-dichlorophenyl)-1-((1s,3r)-3,4-dihydro-3-(hydroxymethyl)-5-(3-hydroxy-3-methylbutyl)-1-methyl-2(1h)-isoquinolinyl)-
  6. Drug

    Ulixertinib

    go.drugbank.com/drugs/DB13930
    Investigational

    It is currently in clinical trials for the treatment of a wide range of tumors. … Ulixertinib is a a novel, reversible, ATP-competitive ERK1/2 inhibitor with high potency and ERK1/2 selectivity [A31474].

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Thiostrepton

    go.drugbank.com/drugs/DB11467
    InvestigationalVet approved

    Thiostrepton is a natural product of the ribosomally synthesized and post-translationally modified peptide class. … Thiostrepton is a natural cyclic oligopeptide antibiotic, derived from several strains of streptomycetes including Streptomyces azureus and Streptomyces laurentii.

  8. Drug

    BMS-214662

    go.drugbank.com/drugs/DB12234
    Investigational

    BMS-214662 has been used in trials studying the treatment of Childhood Myelodysplastic Syndromes, Refractory Anemia With Excess Blasts, Recurrent Adult Acute Myeloid Leukemia, Relapsing Chronic Myelogenous

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  9. Drug

    EGT-101

    go.drugbank.com/drugs/DB17645
    Experimental

    EGT-101 is an adeno-associated viral vector serotype 9 (AAV9) vector-based gene therapy consisting of the human sulfamidase (SGSH) transgene. … Developed by Esteve Pharmaceuticals, it is being investigated for Sanfilippo syndrome type A.[L45919]

  10. Drug

    Bifunctional epoxide hydrolase 2

    go.drugbank.com/drugs/DB15139
    Investigational

    Bifunctional epoxide hydrolase 2 is under investigation in clinical trial NCT00654966 (Evaluation of the Effects of Urotensin-II and Soluble Epoxide Hydrolase Inhibitors on Skin Microvessel Tone in Patients

    Synonyms: Bifunctional epoxide hydrolase 2