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Displaying results 9661 - 9670 of 10000 in total
  1. Drug

    S65487

    go.drugbank.com/drugs/DB17556
    Investigational

    S65487 a potent and selective BCL-2 inhibitor, and a prodrug of S55746.

  2. Drug

    Sovleplenib

    go.drugbank.com/drugs/DB17557
    Investigational

    Sovleplenib is a novel, investigational, selective small molecule inhibitor for oral administration targeting spleen tyrosine kinase (Syk).

  3. Drug

    Evorpacept

    go.drugbank.com/drugs/DB17573
    Investigational

    Evorpacept is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05)).

    Synonyms: A CD47-binding, fusion protein containing a high affinity engineered D1 domain of human signal regulatory protein alpha (SIRPalpha) variant 1 (v1) genetically linked to a modified and inactive Fc domain
  4. Drug

    SS1(dsFv)-PE38

    go.drugbank.com/drugs/DB17579
    Investigational

    SS1(dsFv)-PE38 is a recombinant anti-mesothelin immunotoxin. … SS1(dsFv)-PE38 is under investigation in clinical trial NCT01051934 (A Phase I Trial of SS1 (Dsfv) PE38 With Paclitaxel, Carboplatin, and Bevacizumab in Subjects With Unresectable Non-small Cell Lung Adenocarcinoma

  5. Drug

    Mezigdomide

    go.drugbank.com/drugs/DB17584
    Investigational

    Mezigdomide is under investigation in clinical trial NCT05372354 (A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-986348) in Combination With Other Treatments in Participants

  6. Drug

    CDX-6210

    go.drugbank.com/drugs/DB17610
    Experimental

    CDX-6210 is a modified version of a leucine decarboxylase enzyme from _Planctomycetaceae bacterium_.

  7. Drug

    Ergothioneine

    go.drugbank.com/drugs/DB17614
    Investigational

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Phosphocysteamine

    go.drugbank.com/drugs/DB17640
    Experimental

    Categories: Compounds used in a research, industrial, or household setting
  9. Drug

    GTP-506

    go.drugbank.com/drugs/DB17682
    Experimental

    GTP-506 is a gene therapy formed by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and a therapeutic donor vector that inserts the OTC gene to provide

  10. Drug

    CB-010

    go.drugbank.com/drugs/DB17711
    Investigational

    CB-010 is a CRISPR-edited allogeneic CAR-T cell therapy targeting CD19. It is being investigated for the treatment of follicular lymphoma.[L46158]