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Displaying results 9681 - 9690 of 10000 in total
  1. Drug

    Tolrestat

    go.drugbank.com/drugs/DB02383
    ApprovedWithdrawn

    While it was approved for marketed in several countries, it failed a Phase III trial in the U.S. due to toxicity and never received FDA approval.

  2. Drug

    Hydrogenobyrinic acid

    go.drugbank.com/drugs/DB02460
    Experimental

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds with 4 or More Rings
  3. Drug

    Ghavamiol

    go.drugbank.com/drugs/DB02492
    Experimental

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    1-Deoxy-D-xylulose 5-phosphate

    go.drugbank.com/drugs/DB02496
    Experimental

    The proteins that 1-Deoxy-D-xylulose 5-phosphate targets include 1-Deoxy-D-xylulose 5-phosphate reductoisomerase and pyridoxine 5'-phosphate synthase. 1-Deoxy-D-xylulose 5-phosphate is an intermediate … 1-Deoxy-D-xylulose 5-phosphate is a solid. This compound belongs to the pentose phosphates. These are carbohydrate derivatives containing a pentose substituted by one or more phosphate groups.

    Synonyms: 1-Deoxy-D-xylulose 5-phosphate
  5. Drug

    Thymol

    go.drugbank.com/drugs/DB02513
    ApprovedInvestigational

    A phenol obtained from thyme oil or other volatile oils. It is used as a stabilizer in pharmaceutic preparations. … It has been used for its antiseptic, antibacterial, and antifungal actions, and was formerly used as a vermifuge. (Dorland, 28th ed)

    Mixtures: VICKS VAPORUB BUHARLASAN MERHEM, 1 ADETSynonyms: 5-Methyl-2-(1-Methylethyl)Phenol, 2-isopropyl-5-methylphenol
  6. Drug

    Ditiocarb

    go.drugbank.com/drugs/DB02520
    Investigational

    A chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental animals. It is the main metabolite of DISULFIRAM.

    Categories: Cytochrome P-450 CYP2A6 Inhibitors, Cytochrome P-450 CYP3A Inhibitors
  7. Drug

    Vorinostat

    go.drugbank.com/drugs/DB02546
    ApprovedInvestigational

    Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation for the treatment of cutaneous T cell lymphoma (CTCL), a type of skin cancer, to be used when the disease … A recent study suggested that vorinostat also possesses some activity against recurrent glioblastoma multiforme, resulting in a median overall survival of 5.7 months (compared to 4 - 4.4 months in earlier

    Products: ZOLINZA®VORINOSTAT 100 MG CAPSULAS
  8. Drug

    Hexanoyl-CoA

    go.drugbank.com/drugs/DB02563
    Experimental

    Synonyms: n-hexanoyl-coenzyme A, S-Hexanoyl-coenzym-ACategories: Thioesters of coenzyme A, Heterocyclic Compounds, 2-Ring
  9. Drug

    Peldesine

    go.drugbank.com/drugs/DB02568
    Investigational

    Peldesine is a potent inhibitor of human CCRF-CEM T-cell proliferation. It has undergone phase I trials for the treatment of Human Immunodeficiency Virus (HIV) infections.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingSynonyms: 2-Amino-3,5-dihydro-7-(3-pyridylmethyl)-4H-pyrrolo(3,2-d)pyrimidin-4-one
  10. Drug

    Adenosine Phosphonoacetic Acid

    go.drugbank.com/drugs/DB02607
    Experimental

    Categories: Heterocyclic Compounds, 2-Ring