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Displaying results 9681 - 9690 of 10000 in total
  1. Drug

    Elapegademase

    go.drugbank.com/drugs/DB14712
    Approved

    Elapegademase is a PEGylated recombinant adenosine deaminase. … It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl

    Synonyms: (74-SERINE (C>S),245-THREONINE (A>T))BOS TAURUS ADENOSINE DEAMINASE (BOVINE ADENOSINE AMINOHYDROLASE, EC=3.5.4.4)-(1-356)-PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN AVERAGE OF 13 RESIDUES ARE SUBSTITUTED, -METHOXYPOLY(O
  2. Drug

    Cinazepam

    go.drugbank.com/drugs/DB14715
    Experimental

    Categories: Heterocyclic Compounds, 2-Ring
  3. Drug

    Bentazepam

    go.drugbank.com/drugs/DB14719
    Experimental

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Rebeccamycin

    go.drugbank.com/drugs/DB14729
    Investigational

    Rebeccamycin is a weak topoisomerase I inhibitor isolated from _Nocardia sp_.

    Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 3-Ring
  5. Drug

    Peginterferon lambda-1a

    go.drugbank.com/drugs/DB14767
    Investigational

    Peginterferon Alfa-2a, Plus Ribavirin in Subjects With Genotype 1 Hepatitis C).

  6. Drug

    DCFBC F-18

    go.drugbank.com/drugs/DB14772
    Investigational

    DCFBC F-18 is under investigation in clinical trial NCT02190279 (18F-DCFBC PET/CT in Prostate Cancer).

    Synonyms: DCFBC F-18
  7. Drug

    Lifirafenib

    go.drugbank.com/drugs/DB14773
    Investigational

    Lifirafenib is under investigation in clinical trial NCT03641586 (The Study of BGB-283 in Chinese Subjects With Local Advanced or Metastatic Malignant Solid Tumor).

    Categories: Heterocyclic Compounds, 2-Ring
  8. Drug

    LGD-6972

    go.drugbank.com/drugs/DB14779
    Investigational

    LGD-6972 is under investigation in clinical trial NCT01919684 (Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LGD-6972 in Healthy Subjects and Subjects With Type 2 Diabetes

  9. Drug

    Vofatamab

    go.drugbank.com/drugs/DB14781
    Investigational

    Vofatamab is under investigation in clinical trial NCT02401542 (Dose Escalation, Expansion Study of Vofatamab (B-701) in Treatment of Locally Advanced or Metastatic Urothelial Cell Carcinoma).

  10. Drug

    Tofersen

    go.drugbank.com/drugs/DB14782
    ApprovedInvestigational

    [L46108] Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more than 200 SOD1 mutations documented. … [L46133] Continual FDA approval is contingent on clinical benefits from ongoing trials, particularly the Phase 3 ATLAST study in people with presymptomatic SOD1-ALS.

    Synonyms: DNA, D((2'-O-(2-METHOXYETHYL))M5RC-SP-(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-SP-(2'-O-(2-METHOXYETHYL))RG-(2'-O-(2-METHOXYETHYL))RA-SP-T-SP-A-SP-M5C-SP-A-SP-T-SP-T-SP-T-SP-M5C-SP-T-SP-A-SP, -(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))R