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Displaying results 961 - 970 of 7452 in total
  1. Drug

    Butamben

    go.drugbank.com/drugs/DB11148
    ApprovedWithdrawn

    Butamben is a local anesthetic in the form of n-butyl-p-aminobenzoate. … The FDA removed all parenteral butamben products from the market, possibly due to the poor solubility of this drug.[A254247,L43942]

  2. Drug

    Polyethylene glycol 400

    go.drugbank.com/drugs/DB11077
    ApprovedInvestigational

    PEGylation occurs when PEGs are attached to numerous protein medications, allowing for greater solubility for selected drugs. … It is used in ophthalmic solutions for the relief of burning, irritation and/or discomfort that follows dryness of the eye [L1785].

    Mixtures: Visine ALL DAY COMFORT DRY EYE Relief, Visine for Red Eye CoolCategories: Compounds used in a research, industrial, or household setting
  3. Drug

    Ergocalciferol

    go.drugbank.com/drugs/DB00153
    ApprovedInvestigationalNutraceutical

    Ergocalciferol was isolated for the first time from yeast in 1931 and its structure was elucidated in 1932. … These modifications reduce the affinity of ergocalciferol for the vitamin D binding protein resulting in faster clearance, limits its activation, and alters its catabolism.

    Mixtures: Insur-all Vitamin Supplement, TAMIPOOL FOR INJECTION
  4. Drug

    Tideglusib

    go.drugbank.com/drugs/DB12129
    ApprovedInvestigationalWithdrawn

    Tideglusib is under the investigation for the development of treatments for Alzheimer's disease and for progressive supranuclear palsy. … [A31601] Tideglusib is being developed by the Spanish pharmaceutic company Zeltia group and its current status is withdrawn for the treatment of Alzheimer's disease as of 2012.

  5. Drug

    Entecavir

    go.drugbank.com/drugs/DB00442
    ApprovedInvestigational

    Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use
  6. Drug

    D-alpha-Tocopherol acetate

    go.drugbank.com/drugs/DB14002
    ApprovedNutraceuticalVet approved

    bioavailability out of all of the alpha-tocopherol stereoisomers. … At the moment however, there exists a lack of formal data and evidence to support any such additional indications for vitamin E use.

    Mixtures: Poly-Vi-Flor, Poly-VI-florCategories: Compounds used in a research, industrial, or household setting
  7. Drug

    Ledipasvir

    go.drugbank.com/drugs/DB09027
    Approved

    HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and affecting 72% of all chronic HCV patients [L852]. … of HCV infection is associated with significant long-term health benefits including reduced liver-related damage, improved quality of life, reduced incidence of Hepatocellular Carcinoma, and reduced all-cause

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use
  8. Drug

    Vonoprazan

    go.drugbank.com/drugs/DB11739
    ApprovedInvestigational

    PCABs represent an alternative to proton-pump inhibitors for the treatment of acid-related disorders. … [A253702] In May 2022, the FDA approved the use of vonoprazan in a co-packaged product containing amoxicillin and clarithromycin for the treatment of _H. pylori_ infection.

    Categories: Drugs for Acid Related Disorders, Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)
  9. Drug

    Tazobactam

    go.drugbank.com/drugs/DB01606
    ApprovedInvestigational

    It is combined with [Piperacillin] and [Ceftolozane] for the treatment of a variety of bacterial infections. … In June 2019, ceftolozane-tazobactam was approved by the FDA for treating hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia, which are significant causes of morbidity

    Mixtures: Zerbaxa 1.5g powder for solution for injection, ZERBAXA POWDER FOR SOLUTION FOR INJECTION 1G/0.5GCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  10. Drug

    Fluoxetine

    go.drugbank.com/drugs/DB00472
    ApprovedInvestigationalVet approved

    [A181673] It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies

    Mixtures: PISAURIT FONCategories: Antidepressive Agents Indicated for Depression