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Oteracil
go.drugbank.com/drugs/DB03209ApprovedInvestigationalApproved by the European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with [DB09257] and [DB09256] within the commercially available product "Teysuno". … The main active ingredient in Teysuno is [DB09256], a pro-drug of [DB00544] (5-FU), which is a cytotoxic anti-metabolite drug that acts on rapidly dividing cancer cells.
Sodium hydroxide
go.drugbank.com/drugs/DB11151ApprovedThe use of this compound has been shown to effectively reduce prion levels in an in vitro inactivation assay [A32334]. … Interestingly, sodium hydroxide has been studied for its use in the treatment of prion disease (as occurs in mad cow disease and kuru).
Mixtures: AMINOPLASMAL® 10% E, AMINOPLASMAL® 10% ECategories: Compounds used in a research, industrial, or household settingMepolizumab
go.drugbank.com/drugs/DB06612ApprovedInvestigationalThis indication was subsequently expanded to cover EGPA on December 12, 2017, and HES on September 25, 2020.[L16518] … Mepolizumab was first approved by the FDA on November 4, 2015, as an add-on therapy for severe asthma and marketed under the brand name Nucala by GlaxoSmithKline.
Products: NUCALA SOLUTION FOR INJECTION IN PRE-FILLED PEN 100MG/ML, Nucala 100mg/ml Solution for Injection in pre-filled pen (Autoinjector)Cantharidin
go.drugbank.com/drugs/DB12328ApprovedInvestigationalAvailable synthetically since the 1950s, topical applications of cantharidin have been used predominantly as a treatment for cutaneous warts since that time. … [A32892] Nevertheless, it gained its first FDA approval on Jul 21, 2023, under the brand name YCANTH™ by Verrica Pharmaceuticals for the treatment of molluscum contagiosum in adult and pediatric patients
Categories: Compounds used in a research, industrial, or household settingIfosfamide
go.drugbank.com/drugs/DB01181ApprovedInvestigationalIt is active as an alkylating agent and an immunosuppressive agent.
Products: IFO-CELL N 1000, IFO-cell N 1000; Solution for Infusion (1000mg per vial)Triethylenetetramine
go.drugbank.com/drugs/DB06824ApprovedInvestigational[A19333] Initially approved by the FDA in 1985 as a second-line treatment for Wilson's disease,[A19334] TETA is currently indicated to treat adults with stable Wilson’s disease who are de-coppered and … TETA was first developed in Germany in 1861 and its chelating properties were first recognized in 1925.
Categories: Compounds used in a research, industrial, or household settingBenzylpenicillin
go.drugbank.com/drugs/DB01053ApprovedInvestigationalVet approvedThe natural penicillins may also be used as first or second line agents against susceptible gram positive aerobic bacilli such as *Bacillus anthracis*, *Corynebacterium diphtheriae*, and *Erysipelothrix … Penicillin G may also be used in some cases as prophylaxis against susceptible organisms.
Mixtures: BENZAPEN 6.3.3 IM ENJ TOZ ICEREN FLAKON, 1 ADET, BENZAPEN 6.3.3 IM ENJ TOZ ICEREN FLAKON, 1 ADETProducts: Novo-pen G 500Human Rho(D) immune globulin
go.drugbank.com/drugs/DB11597ApprovedRho (D) immune globulin is available as a sterile, lyophilized or liquid gamma globulin (IgG) fraction containing antibodies to the Rh0 (D) antigen (D antigen) under the name Rhophylac (IM/IV). … It was approved by FDA as treatment for suppression of rhesus (Rh) isoimmunization or chronic immune thrombocytopenic purpura (ITP) in adults.
Products: rhophylac 300 microgram/2ml,solution for injection in pre-filled syringeDoxercalciferol
go.drugbank.com/drugs/DB06410ApprovedInvestigationalDoxercalciferol is indicated for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease on dialysis, as well as for the treatment of secondary hyperparathyroidism in patients … Doxercalciferol is a synthetic vitamin D2 analog that undergoes metabolic activation in vivo to form 1α,25-dihydroxyvitamin D2 (1α,25-(OH)2D2), a naturally occurring, biologically active form of vitamin
Categories: Bone Density Conservation AgentsTerpin hydrate
go.drugbank.com/drugs/DB13163ApprovedWithdrawnIt was popular in the United States since the late nineteenth century, but was removed from marketed medications in the 1990s after FDA stated that "based on evidence currently available, there are inadequate … Elixirs of terpin hydrate are still available to patients as prescription medications to be prepared by specialty compounding pharmacies.