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Displaying results 9691 - 9700 of 10000 in total
  1. Drug

    Fexuprazan

    go.drugbank.com/drugs/DB16078
    Investigational

    Abeprazan is under investigation in clinical trial NCT04341454 (Study to Evaluate the Efficacy and Safety of DWP14012 in Patients With Acute or Chronic Gastritis).

    Synonyms: 1H-PYRROLE-3-METHANAMINE, 5-(2,4-DIFLUOROPHENYL)-1-((3-FLUOROPHENYL)SULFONYL)-4-METHOXY-N-METHYL-, 5-(2,4-DIFLUOROPHENYL)-1-((3-FLUOROPHENYL)SULFONYL)-4-METHOXY-N-METHYL-1H-PYRROLE-3-METHANAMINECategories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Lazertinib

    go.drugbank.com/drugs/DB16216
    ApprovedInvestigational

    Lazertinib is an oral, third-generation, epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI).

    Categories: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors, Cytochrome P-450 SubstratesSynonyms: 2-PROPENAMIDE, N-(5-((4-(4-((DIMETHYLAMINO)METHYL)-3-PHENYL-1H-PYRAZOL-1-YL)-2-PYRIMIDINYL)AMINO)-4-METHOXY-2-(4-MORPHOLINYL)PHENYL)-, N-(5-((4-(4-((DIMETHYLAMINO)METHYL)-3-PHENYL-1H-PYRAZOL-1-YL)PYRIMIDIN-2-YL)AMINO)-4-METHOXY-2-MORPHOLINOPHENYL)ACRYLAMIDE
  3. Drug

    Nevanimibe

    go.drugbank.com/drugs/DB16254
    Investigational

    Nevanimibe is under investigation in clinical trial NCT03053271 (A Study of ATR-101 for the Treatment of Endogenous Cushing's Syndrome).

  4. Drug

    Novaferon

    go.drugbank.com/drugs/DB16483
    Investigational

  5. Drug

    Tetramisole

    go.drugbank.com/drugs/DB16561
    Investigational

    Tetramisole is an anthelmintic agent.

    Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Almonertinib

    go.drugbank.com/drugs/DB16640
    ApprovedInvestigational

    [A231859, A231864, A231869] Unlike other third-generation EGFR TKIs, almonertinib is a pyrimidine-based drug that forms a covalent bond to the binding site of the EGFR tyrosine kinase domain. … Almonertinib is a third-generation EGFR tyrosine kinase inhibitor targeting EGFR-sensitizing and T790M resistance mutations.

    Categories: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors, MATE 1 InhibitorsSynonyms: 2-Propenamide, N-[5-[[4-(1-cyclopropyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxyphenyl]-, N-[5-[[4-(1-Cyclopropyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxyphenyl]-2-propenamide
  7. Drug

    Acesulfame

    go.drugbank.com/drugs/DB16868
    Investigational

    Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    TAK-418 free base

    go.drugbank.com/drugs/DB16939
    Investigational

    Synonyms: 5-((1R,2R)-2-((Cyclopropylmethyl)amino)cyclopropyl)-N-(tetrahydro-2H-pyran-4-yl)thiophene-3-carboxamideCategories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Chelerythrine

    go.drugbank.com/drugs/DB17024
    Experimental

    A benzophenanthridine alkaloid evaluated as a kinase-inhibitor.[A252982]

    Categories: Heterocyclic Compounds, 3-Ring, Heterocyclic Compounds with 4 or More RingsSynonyms: 1,2-dimethoxy-12-methyl(1,3)dioxolo)4',5':4,5)benzo(1,2-c)phenanthridinium, (1,3)benzodioxolo(5,6-c)phenanthridinium, 1,2-dimethoxy-12-methyl-
  10. Drug

    AZD2066

    go.drugbank.com/drugs/DB17078
    Investigational

    Synonyms: Pyridine, 4-(5-((1r)-1-(5-(3-chlorophenyl)-3-isoxazolyl)ethoxy)-4-methyl-4h-1,2,4-triazol-3-yl)-Categories: Receptor, Metabotropic Glutamate 5, antagonists & inhibitors, Heterocyclic Compounds, 1-Ring