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Smallpox (Vaccinia) Vaccine, Live
go.drugbank.com/drugs/DB14711ApprovedInvestigationalThe New York City Board of Health strain of _Vaccinia_ is a viral strain used as a component of some smallpox vaccinations. … [L12747] ACAM2000, a percutaneously administered smallpox vaccine that was approved by the FDA in 2007, contains live antigens of this strain.
Synonyms: Vaccinia virus live antigen, BElapegademase
go.drugbank.com/drugs/DB14712ApprovedElapegademase is a PEGylated recombinant adenosine deaminase. … It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl
Synonyms: (74-SERINE (C>S),245-THREONINE (A>T))BOS TAURUS ADENOSINE DEAMINASE (BOVINE ADENOSINE AMINOHYDROLASE, EC=3.5.4.4)-(1-356)-PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN AVERAGE OF 13 RESIDUES ARE SUBSTITUTED, -METHOXYPOLY(ORebeccamycin
go.drugbank.com/drugs/DB14729InvestigationalRebeccamycin is a weak topoisomerase I inhibitor isolated from _Nocardia sp_.
Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 3-RingPeginterferon lambda-1a
go.drugbank.com/drugs/DB14767InvestigationalPeginterferon Alfa-2a, Plus Ribavirin in Subjects With Genotype 1 Hepatitis C).
DCFBC F-18
go.drugbank.com/drugs/DB14772InvestigationalDCFBC F-18 is under investigation in clinical trial NCT02190279 (18F-DCFBC PET/CT in Prostate Cancer).
Synonyms: DCFBC F-18Lifirafenib
go.drugbank.com/drugs/DB14773InvestigationalLifirafenib is under investigation in clinical trial NCT03641586 (The Study of BGB-283 in Chinese Subjects With Local Advanced or Metastatic Malignant Solid Tumor).
Categories: Heterocyclic Compounds, 2-RingLGD-6972
go.drugbank.com/drugs/DB14779InvestigationalLGD-6972 is under investigation in clinical trial NCT01919684 (Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LGD-6972 in Healthy Subjects and Subjects With Type 2 Diabetes
Vofatamab
go.drugbank.com/drugs/DB14781InvestigationalVofatamab is under investigation in clinical trial NCT02401542 (Dose Escalation, Expansion Study of Vofatamab (B-701) in Treatment of Locally Advanced or Metastatic Urothelial Cell Carcinoma).