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Zebularine
go.drugbank.com/drugs/DB03068ExperimentalAlso shown to inhibit DNA methylation and tumor growth both in vitro and in vivo. … It acts as a transition state analog inhibitor of cytidine deaminase by binding to the active site as covalent hydrates.
TNP-2092
go.drugbank.com/drugs/DB16312InvestigationalTNP-2092 is under investigation in clinical trial NCT03964493 (TNP-2092 to Treat Acute Bacterial Skin and Skin Structure Infection).
Tetraarsenic tetrasulfide
go.drugbank.com/drugs/DB19141InvestigationalTetraarsenic tetrasulfide is under investigation in clinical trial NCT05682131 (South China Children Cancer Group - Relapsed-acute Lymphoblastic Leukemia 2022 Protocol).
Substance P
go.drugbank.com/drugs/DB19198InvestigationalSubstance P is under investigation in clinical trial NCT03738878 (Mechanism(s) Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 1).
Mesenchymal stem cell-derived exosomes
go.drugbank.com/drugs/DB24445InvestigationalMesenchymal Stem Cell-Derived Exosomes is under investigation in clinical trial NCT07183384 (MSC Exosome Therapy for Post-Preeclampsia Endothelial Dysfunction). … Mesenchymal Stem Cell-Derived Exosomes is a biologic drug.
1-Deoxy-D-xylulose 5-phosphate
go.drugbank.com/drugs/DB02496Experimentalin the non-mevalonate pathway. … The proteins that 1-Deoxy-D-xylulose 5-phosphate targets include 1-Deoxy-D-xylulose 5-phosphate reductoisomerase and pyridoxine 5'-phosphate synthase. 1-Deoxy-D-xylulose 5-phosphate is an intermediate
FRAX597
go.drugbank.com/drugs/DB31734ExperimentalFRAX597 is a small molecule drug that inhibits the p21-activated kinases (PAKs).[A274673, A274678]
Risovalisib
go.drugbank.com/drugs/DB21474InvestigationalRisovalisib is under investigation in clinical trial NCT05043922 (A Study to Evaluate the Efficacy and Safety of CYH33 in Patients With Recurrent/Persistent Ovary Clear Cell Carcinoma). … Risovalisib is a small molecule drug.
Limonene, (+/-)-
go.drugbank.com/drugs/DB19146InvestigationalLimonene, (+/-)- is under investigation in clinical trial NCT05525260 (Limonene for Pulmonary Nodule Chemoprevention).
Phenazepam
go.drugbank.com/drugs/DB19164InvestigationalPhenazepam is under investigation in clinical trial NCT03017430 (Pregabalin for Opiate Withdrawal Syndrome).