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BMS-741672
go.drugbank.com/drugs/DB19004InvestigationalBMS-741672 is under investigation in clinical trial NCT00699790 (Proof of Confidence Study of CCR2 Antagonist (BMS-741672) in Insulin Resistance).
Synonyms: N-(5-(ISOPROPYL(METHYL)AMINO)-2-(2-OXO-3-((6-(TRIFLUOROMETHYL)QUINAZOLIN-4-YL)AMINO)PYRROLIDIN-1-YL)CYCLOHEXYL)METHANESULFONAMIDEAtuzaginstat
go.drugbank.com/drugs/DB19030InvestigationalAtuzaginstat is under investigation in clinical trial NCT03823404 (GAIN Trial: Phase 2/3 Study of COR388 in Subjects With Alzheimer's Disease).
Synonyms: Cyclopentanecarboxamide, n-((1s)-5-amino-1-(2-(2,3,6-trifluorophenoxy)acetyl)pentyl)-, N-((3s)-7-amino-2-oxo-1-(2,3,6- trifluorophenoxy)heptan-3-yl)cyclopentanecarboxamideMethylone
go.drugbank.com/drugs/DB19192InvestigationalMethylone is under investigation in clinical trial NCT05741710 (A Study to Assess the use of Methylone in the Treatment of PTSD).
Synonyms: 3,4-methylenedioxy-n-methylcathinoneONO-5334
go.drugbank.com/drugs/DB19206InvestigationalONO-5334 is under investigation in clinical trial NCT00532337 (Controlled Study of ONO-5334 in Postmenopausal Women With Osteopenia or Osteoporosis).
Synonyms: N-((1S)-3-((2Z)-2-((4R)-3,4-DIMETHYL-1,3-THIAZOLIDIN-2-YLIDENE)HYDRAZINO)-2,3-DIOXO-1-(TETRAHYDRO-2H-PYRAN-4YL)PROPYL)CYCLOHEPTANECARBOXAMIDEVilastobart
go.drugbank.com/drugs/DB19327InvestigationalVilastobart is under investigation in clinical trial NCT04896697 (Vilastobart (XTX101) Monotherapy and Vilastobart and Atezolizumab Combination Therapy in Advanced Solid Tumors).
Synonyms: heavy chain humanized (1-449) [VH (Homo sapiens IGHV1-69*08 (84.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT[8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, D12, L14, G1v7 CH2 D3Verdinexor
go.drugbank.com/drugs/DB12207InvestigationalKpt 335 is under investigation in clinical trial NCT02431364 (Trial of Safety and Tolerability of Oral Verdinexor (Verdinexor) in Healthy Adults).
SB 11285
go.drugbank.com/drugs/DB17511Investigational[L45123] SB 11285 is under investigation in clinical trial NCT04096638 (Evaluating Safety and Efficacy of SB 11285 Alone and in Combination With Atezolizumab in Patients With Advanced Solid Tumors).
FF-10501-01
go.drugbank.com/drugs/DB17554Investigational[A257306] FF-10501-01 is under investigation in clinical trial NCT03486353 (A Study of FF-10501-01 in Combination With Azacitidine in Patients With Myelodysplastic Syndrome).
Dihydroxyacetone
go.drugbank.com/drugs/DB01775ExperimentalIt is readily phosphorylated to dihydroxyacetone phosphate by triokinase in erythrocytes. In combination with naphthoquinones it acts as a sunscreening agent. [PubChem] … Its addition to blood preservation solutions results in better maintenance of 2,3-diphosphoglycerate levels during storage.
Perenostobart
go.drugbank.com/drugs/DB18602InvestigationalPerenostobart is an alpha-CD39 IgG4 monoclonal antibody.