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Displaying results 9741 - 9750 of 10000 in total
  1. Drug

    PF-04634817

    go.drugbank.com/drugs/DB14955
    Investigational

    PF-04634817 is under investigation in clinical trial NCT01140672 (A Multiple Dose Study To Determine Safety, Tolerability, and Pharmacokinetics Of PF-04634817 In Healthy Adult Subjects).

    Categories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Selicrelumab

    go.drugbank.com/drugs/DB14958
    Investigational

    Selicrelumab is under investigation in clinical trial NCT01008527 (Phase I Oncovir Poly IC:LC and NY-ESO-1/gp100).

  3. Drug

    Seltorexant

    go.drugbank.com/drugs/DB14961
    Investigational

    Seltorexant is under investigation in clinical trial NCT03494907 (A Study to Evaluate the Effects of Single-dose Seltorexant on Electrocardiogram Intervals in Healthy Adult Participants).

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Trastuzumab deruxtecan

    go.drugbank.com/drugs/DB14962
    ApprovedInvestigational

    Trastuzumab deruxtecan is a HER2-directed antibody attached to a topoisomerase inhibitor that is approved for use in certain types of treatment-resistant HER2-positive cancers.

    Synonyms: T-DXd, T- DXdCategories: MATE 2 Substrates, P-glycoprotein substrates
  5. Drug

    Narnatumab

    go.drugbank.com/drugs/DB14964
    Investigational

    Narnatumab is under investigation in clinical trial NCT01119456 (A Study of IMC-RON8 in Advanced Solid Tumors).

  6. Drug

    Iomazenil

    go.drugbank.com/drugs/DB14971
    Investigational

    Iomazenil is under investigation in clinical trial NCT01590277 (Ability of Partial Inverse Agonist, Iomazenil, to Block Ethanol Effects in Humans).

    Categories: Heterocyclic Compounds, 2-Ring
  7. Drug

    Bivalirudin

    go.drugbank.com/drugs/DB00006
    ApprovedInvestigational

    Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin.

    Products: ANGIOMAX® POLVO LIOFILIZADO PARA RECONSTRUIR A SOLUCIÓN INYECTABLE (50MG/ML), OBIVADIN 250 MG IV ENJEKSIYON/INFÜZYON IÇIN LIYOFILIZE TOZ, 1 ADET
  8. Drug

    Desmopressin

    go.drugbank.com/drugs/DB00035
    ApprovedInvestigational

    Desmopressin, also known as 1-deamino-8-D-arginine vasopressin (DDAVP), is a synthetic analogue of the natural posterior pituitary hormone arginine vasopressin (AVP) [A275458, L56105]. … It was designed through two primary chemical modifications of the natural hormone: the deamination of 1-cysteine and the substitution of L-arginine with D-arginine at the 8th position [A31661, A275458]

    Synonyms: 1 deamino 8 D argininevasopressin, 1-(3-mercaptopropionic acid)-8-D-arginine-vasopressinProducts: EMOSINT® 4 MCG /0.5 ML, MINIRIN (4 UG/ML)
  9. Drug

    Cetrorelix

    go.drugbank.com/drugs/DB00050
    ApprovedInvestigational

    Cetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH).

    Products: CETROTIDE® 0.25MG, CETROTIDE 3 MG.
  10. Drug

    Cyclosporine

    go.drugbank.com/drugs/DB00091
    ApprovedInvestigationalVet approved

    Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions.

    Synonyms: Cyclosporin A, Cyclosporine ACategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index