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Displaying results 9741 - 9750 of 10000 in total
  1. Drug

    Avacopan

    go.drugbank.com/drugs/DB15011
    ApprovedInvestigational

    Anti-neutrophil cytoplasmic (auto)antibody (ANCA)-associated vasculitis (AAV) is a rare (estimated incidence of 3 cases per 100,000 per year) form of "pauci-immune" systemic small-vessel vasculitis typified … [A240249, A240254] Despite complex pathophysiology, studies over the past ~2 decades have identified a key role for the alternative complement pathway and, in particular, the interaction between the anaphylatoxin

    Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  2. Drug

    Farampator

    go.drugbank.com/drugs/DB15012
    Investigational

    Farampator is under investigation in clinical trial NCT00113022 (Org 24448 to Treat Major Depression).

    Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Gremubamab

    go.drugbank.com/drugs/DB15014
    Investigational

    Gremubamab is under investigation in clinical trial NCT02255760 (Phase 1 Randomized Double-blind Placebo Controlled Study to Evaluate Safety and PK of MEDI3902 in Healthy Adults).

  4. Drug

    Mongersen

    go.drugbank.com/drugs/DB15019
    Investigational

    Mongersen is under investigation in clinical trial NCT02957474 (A Study to Evaluate the Effect of Food, Formulation Strength, and a Proton Pump Inhibitor on GED 0301 Pharmacokinetics in Healthy Adult Subjects

  5. Drug

    BMS-791826

    go.drugbank.com/drugs/DB15023
    Investigational

    BMS-791826 is under investigation in clinical trial NCT03198013 (A Study of Pharmacokinetics (PK) and Pharmacodynamics (PD) in Relation to Prednisolone in Healthy Males).

    Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Apararenone

    go.drugbank.com/drugs/DB15024
    Investigational

    Apararenone is under investigation in clinical trial NCT02531568 (Drug Interaction Study of Warfarin and MT-3995).

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    CXA-10

    go.drugbank.com/drugs/DB15026
    Investigational

    CXA-10 is under investigation in clinical trial NCT03422510 (FIRSTx - A Study of Oral CXA-10 in Primary Focal Segmental Glomerulosclerosis (FSGS)).

    Synonyms: 10-nitro-9(E)-octadec-9-enoic acid
  8. Drug

    AZD-8186

    go.drugbank.com/drugs/DB15029
    Investigational

    AZD-8186 is under investigation in clinical trial NCT03218826 (PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot Be Removed by Surgery).

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  9. Drug

    Foscenvivint

    go.drugbank.com/drugs/DB15034
    Investigational

    PRI-724 is under investigation in clinical trial NCT03620474 (Safety and Effectiveness of PRI-724 for Hepatitis C or B Virus Derived Liver Cirrhosis).

    Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Litoxetine

    go.drugbank.com/drugs/DB15038
    Investigational

    Litoxetine is under investigation in clinical trial NCT03397771 (DBPC Trial to Evaluate the Safety, Tolerability and Efficacy of Oral Litoxetine in Subjects With Urinary Incontinence).

    Categories: Heterocyclic Compounds, 1-Ring