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Foscenvivint
go.drugbank.com/drugs/DB15034InvestigationalPRI-724 is under investigation in clinical trial NCT03620474 (Safety and Effectiveness of PRI-724 for Hepatitis C or B Virus Derived Liver Cirrhosis).
25-desacetylrifapentine
go.drugbank.com/drugs/DB15213Investigational25-desacetylrifapentine is under investigation in clinical trial NCT00023387 (TBTC Study 25PK: Intensive Pharmacokinetic Study of Three Doses of Rifapentine and 25-Desacetyl Rifapentine).
AN2898
go.drugbank.com/drugs/DB16039InvestigationalAN2898 is under investigation in clinical trial NCT01301508 (Efficacy and Safety of AN2898 and AN2728 Topical Ointments to Treat Mild-to-moderate Atopic Dermatitis).
PT-2385
go.drugbank.com/drugs/DB16055InvestigationalPT-2385 is under investigation in clinical trial NCT03108066 (PT2385 for the Treatment of Von Hippel-lindau Disease-associated Clear Cell Renal Cell Carcinoma).
GED-0507-34-Levo
go.drugbank.com/drugs/DB16109InvestigationalGED-0507-34-Levo is under investigation in clinical trial NCT02808390 (Efficacy and Safety Study of Ged-0507-34-levo for Treatment of UC).
Latrunculin A
go.drugbank.com/drugs/DB02621InvestigationalLatrunculin A is an actin binding macrolide purified from the red sea sponge Latrunculia magnifica. It is under investigation for the treatment of cancer. … It disrupts actin polymerization, prevents mitotic spindle formation and thus cell replication.
Galicaftor
go.drugbank.com/drugs/DB14894Investigationalin Patients With Cystic Fibrosis.). … Galicaftor is under investigation in clinical trial NCT03540524 (A Study Looking at the Safety, Tolerability and Efficacy of the Combination of the Study Drugs GLPG2451 and GLPG2222 With or Without GLPG2737
KER-047
go.drugbank.com/drugs/DB19111InvestigationalKER-047 is under investigation in clinical trial NCT05927012 (A Study to Evaluate the Safety and Preliminary Efficacy of a Response-guided Dose Titration of KER-047 in the Treatment of Functional IDA (
Ulevostinag
go.drugbank.com/drugs/DB14721Investigationalfactor-kappa B (NF-kB) and interferon regulatory factor 3 (IRF3) in immune cells in the tumor microenvironment; this leads to the production of pro-inflammatory cytokines, including interferons (IFNs) … This results in a CTL-mediated immune response against tumor cells and causes tumor cell lysis. [L4741]
Piroctone
go.drugbank.com/drugs/DB15946InvestigationalPiroctone olamine is used in combination with other substances as a part of shampoo effectively reduced the amount of dandruff and, at the same time, provided hair conditioning advantages. … Recently was shown, that piroctone olamine could induce apoptosis and possessed a significant in vivo effect against myeloma.[L34189]