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Sotagliflozin
go.drugbank.com/drugs/DB12713ApprovedInvestigational[A244470,A244499] Sotagliflozin was approved by the EMA under the brand name "Zynquista" on April 26, 2019, for the treatment of type 1 diabetes.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesPF-00610355
go.drugbank.com/drugs/DB11871InvestigationalPF-00610355 has been used in trials studying the treatment of Lung Disease, Moxifloxacin, Pulmonary Disease, Asthma, Bronchial, and Bronchial Diseases, among others.
Ferrous bisglycinate
go.drugbank.com/drugs/DB11210ApprovedFerrous bisglycinate is a chelate that is used as a source of dietary iron. Forming a ring structure when reacting with glycine, ferrous bisglycinate acts as both a chelate and a nutritionally functional . It is found in foods for food e...
Mixtures: PR Natal 430, PR Natal 400Cetuximab
go.drugbank.com/drugs/DB00002ApprovedInvestigational[A227963] Approved by the FDA in February 2004 under the brand name ERBITUX, cetuximab is used for the treatment of head and neck cancer and metastatic, KRAS wild-type colorectal cancer, and metastatic
Etrasimod
go.drugbank.com/drugs/DB14766ApprovedInvestigational[A261831] Etrasimod was approved on October 13, 2023, by the FDA under the brand name VELSIPITY for the treatment of adults with moderately to severely active ulcerative colitis.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesAzilsartan medoxomil
go.drugbank.com/drugs/DB08822ApprovedInvestigational[A232863] Azilsartan medoxomil is marketed under the brand name Edarbi. It is used to treat hypertension as monotherapy or in combination with other antihypertensive drugs.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesMannitol
go.drugbank.com/drugs/DB00742ApprovedInvestigationalMannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol elevates blood plasma osmolality, resulting in enhanced flow of water from tissue...
Mixtures: CPD/ADSOL Red Cell Preservation Solution System (PL 2209), CPD/ADSOL Red Cell Preservation Solution System (PL 2209)Categories: P-glycoprotein substratesPF-03882845
go.drugbank.com/drugs/DB11814InvestigationalPF-03882845 has been used in trials studying the basic science of Diabetes Mellitus, Type 2 and Type 2 Diabetic Nephropathy.
Tomivosertib
go.drugbank.com/drugs/DB15219InvestigationalTomivosertib is under investigation in clinical trial NCT03318562 (A PD Study of Oral eFT508 in Subjects With Advanced TNBC and HCC).