This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Alcloxa
DrugBank Accession Number
DB11205
Background

Not Available

Type
Small Molecule
Groups
Approved
Structure
Weight
Average: 314.55
Monoisotopic: 313.9790533
Chemical Formula
C4H9Al2ClN4O7
Synonyms
  • Alcloxa
  • Alcloxum
  • Aluminium chlorohydroxyallantoinate
  • Aluminum chlorhydroxy allantoinate
  • Aluminum chlorohydroxy allantoinate
  • Chlorhydroxyaluminum allantoinate
  • Dialuminum tetrahydroxychloro allantoinate
External IDs
  • RC 173
  • RC-173

Pharmacology

Indication

Not Available

Reduce drug development failure rates
Build, train, & validate machine-learning models
with evidence-based and structured datasets.
See how
Build, train, & validate predictive machine-learning models with structured datasets.
See how
Associated Conditions
Contraindications & Blackbox Warnings
Avoid life-threatening adverse drug events
Improve clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.
Learn more
Avoid life-threatening adverse drug events & improve clinical decision support.
Learn more
Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Improve decision support & research outcomes
With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.
Learn more
Improve decision support & research outcomes with our structured adverse effects data.
Learn more
Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
  • Take after a meal. Alcloxa is an ingredient used in toothpaste and brushing teeth after each meal is recommended.

Products

Drug product information from 10+ global regions
Our datasets provide approved product information including:
dosage, form, labeller, route of administration, and marketing period.
Access now
Access drug product information from over 10 global regions.
Access now
Active Moieties
NameKindUNIICASInChI Key
Allantoinunknown344S277G0Z97-59-6POJWUDADGALRAB-UHFFFAOYSA-N
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Exoden Cure PowderPowder0.16 g/100gTopicalLifeon Corp.2021-03-09Not applicableUS flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
28tak Gum Care ToothAlcloxa (0.12 g/120g) + Aminocaproic acid (0.12 g/120g) + Calcium phosphate, dibasic (0.12 g/120g) + Calcium carbonate (36.0 g/120g)Paste, dentifriceOralElmeditec Co.,Ltd2018-07-01Not applicableUS flag
Clean Breath ToothAlcloxa (0.06 g/100g) + Aminocaproic acid (0.06 g/100g) + Calcium phosphate, dibasic (0.07 g/100g) + Calcium carbonate (36 g/100g)Paste, dentifriceDentalK.Boeun Pharmaceutical Co.,Ltd.2021-01-01Not applicableUS flag
Clean Breath ToothAlcloxa (0.06 g/100g) + Aminocaproic acid (0.06 g/100g) + Calcium phosphate, dibasic (0.07 g/100g) + Calcium carbonate (36 g/100g)Paste, dentifriceDentalK.Boeun Pharmaceutical Co.,Ltd.2021-11-30Not applicableUS flag
Clean Breath ToothAlcloxa (0.06 g/100g) + Aminocaproic acid (0.06 g/100g) + Calcium phosphate, dibasic (0.07 g/100g) + Calcium carbonate (36 g/100g)Paste, dentifriceDentalK.Boeun Pharmaceutical Co.,Ltd.2021-05-01Not applicableUS flag
Divinetree Ssak Shark Kids ToothAlcloxa (0.08 g/50g) + Silicon dioxide (6.50 g/50g)Paste, dentifriceOralK.biocos2019-11-01Not applicableUS flag
Dr.EL GUM CARE TOOTHAlcloxa (0.1 g/100g) + Aminocaproic acid (0.1 g/100g) + Calcium phosphate, dibasic (0.1 g/100g) + Calcium carbonate (30 g/100g)Paste, dentifriceDentalDr. EL CO., LTD.2019-08-01Not applicableUS flag
Dr.LORD Green Propol ToothAlcloxa (0.1 g/100g) + Aminocaproic acid (0.1 g/100g) + Silicon dioxide (17.0 g/100g)Paste, dentifriceOralRed 992022-03-01Not applicableUS flag
Exoden CavityAlcloxa (0.16 g/100g) + Silicon dioxide (15 g/100g) + Sodium fluorophosphate (0.76 g/100g)PasteTopicalLifeon Corp.2021-03-10Not applicableUS flag
Exoden GumAlcloxa (0.16 g/100g) + Silicon dioxide (15 g/100g)PasteTopicalLifeon Corp.2021-03-12Not applicableUS flag
Exoden WhiteAlcloxa (0.16 g/100g) + Silicon dioxide (15 g/100g)PasteTopicalLifeon Corp.2021-03-12Not applicableUS flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
28tak Gum Care ToothAlcloxa (0.12 g/120g) + Aminocaproic acid (0.12 g/120g) + Calcium phosphate, dibasic (0.12 g/120g) + Calcium carbonate (36.0 g/120g)Paste, dentifriceOralElmeditec Co.,Ltd2018-07-01Not applicableUS flag
Clean Breath ToothAlcloxa (0.06 g/100g) + Aminocaproic acid (0.06 g/100g) + Calcium phosphate, dibasic (0.07 g/100g) + Calcium carbonate (36 g/100g)Paste, dentifriceDentalK.Boeun Pharmaceutical Co.,Ltd.2021-11-30Not applicableUS flag
Clean Breath ToothAlcloxa (0.06 g/100g) + Aminocaproic acid (0.06 g/100g) + Calcium phosphate, dibasic (0.07 g/100g) + Calcium carbonate (36 g/100g)Paste, dentifriceDentalK.Boeun Pharmaceutical Co.,Ltd.2021-01-01Not applicableUS flag
Clean Breath ToothAlcloxa (0.06 g/100g) + Aminocaproic acid (0.06 g/100g) + Calcium phosphate, dibasic (0.07 g/100g) + Calcium carbonate (36 g/100g)Paste, dentifriceDentalK.Boeun Pharmaceutical Co.,Ltd.2021-05-01Not applicableUS flag
Divinetree Ssak Shark Kids ToothAlcloxa (0.08 g/50g) + Silicon dioxide (6.50 g/50g)Paste, dentifriceOralK.biocos2019-11-01Not applicableUS flag
Dr.EL GUM CARE TOOTHAlcloxa (0.1 g/100g) + Aminocaproic acid (0.1 g/100g) + Calcium phosphate, dibasic (0.1 g/100g) + Calcium carbonate (30 g/100g)Paste, dentifriceDentalDr. EL CO., LTD.2019-08-01Not applicableUS flag
Dr.LORD Green Propol ToothAlcloxa (0.1 g/100g) + Aminocaproic acid (0.1 g/100g) + Silicon dioxide (17.0 g/100g)Paste, dentifriceOralRed 992022-03-01Not applicableUS flag
Exoden CavityAlcloxa (0.16 g/100g) + Silicon dioxide (15 g/100g) + Sodium fluorophosphate (0.76 g/100g)PasteTopicalLifeon Corp.2021-03-10Not applicableUS flag
Exoden Cure PowderAlcloxa (0.16 g/100g)PowderTopicalLifeon Corp.2021-03-09Not applicableUS flag
Exoden GumAlcloxa (0.16 g/100g) + Silicon dioxide (15 g/100g)PasteTopicalLifeon Corp.2021-03-12Not applicableUS flag

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
18B8O9DQA2
CAS number
1317-25-5
InChI Key
IMZDRXBSGZPLDE-UHFFFAOYSA-H
InChI
InChI=1S/C4H6N4O3.2Al.ClH.4H2O/c5-3(10)6-1-2(9)8-4(11)7-1;;;;;;;/h1H,(H5,5,6,7,8,9,10,11);;;1H;4*1H2/q;2*+3;;;;;/p-6
IUPAC Name
dialuminium(3+) 4-(carbamoylamino)-2,5-dioxoimidazolidin-1-ide chloride tetrahydroxide
SMILES
[OH-].[OH-].[OH-].[OH-].[Al+3].[Al+3].[Cl-].NC(=O)NC1NC(=O)[N-]C1=O

References

General References
Not Available
ChemSpider
32698939
RxNav
1305554
Wikipedia
Alcloxa

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Paste, dentifriceOral
PasteTopical
PowderTopical0.16 g/100g
PasteOral
Paste, dentifriceTopical
CreamTopical
Gel, dentifriceOral
Paste, dentifriceDental
LiquidTopical
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility2.35 mg/mLALOGPS
logP-1.4ALOGPS
logP-2.4Chemaxon
logS-2ALOGPS
pKa (Strongest Acidic)7.95Chemaxon
pKa (Strongest Basic)-3.4Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count4Chemaxon
Hydrogen Donor Count3Chemaxon
Polar Surface Area110.52 Å2Chemaxon
Rotatable Bond Count1Chemaxon
Refractivity31.22 m3·mol-1Chemaxon
Polarizability12.54 Å3Chemaxon
Number of Rings1Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created at December 03, 2015 16:51 / Updated at September 28, 2021 21:54