Alcloxa

Identification

Generic Name

Alcloxa

DrugBank Accession Number

DB11205

Background

Not Available

Type

Small Molecule

Groups

Approved

Structure

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MOLSDFPDBSMILESInChI

Similar Structures

Structure for Alcloxa (DB11205)

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Weight

Average: 314.55
Monoisotopic: 313.9790533

Chemical Formula

C₄H₉Al₂ClN₄O₇

Synonyms

• Alcloxa
• Alcloxum
• Aluminium chlorohydroxyallantoinate
• Aluminum chlorhydroxy allantoinate
• Aluminum chlorohydroxy allantoinate
• Chlorhydroxyaluminum allantoinate
• Dialuminum tetrahydroxychloro allantoinate

External IDs

• RC 173
• RC-173

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Pharmacology

Indication

Not Available

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Associated Conditions

Indication Type	Indication	Combined Product Details	Approval Level	Age Group	Patient Characteristics	Dose Form
Used in combination to manage	Dental cavity	Combination Product in combination with: Silicon dioxide (DB11132)	••• •••

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Pharmacodynamics

Not Available

Mechanism of action

Not Available

Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism

Not Available

Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects

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Toxicity

Not Available

Pathways

Not Available

Pharmacogenomic Effects/ADRs

Not Available

Interactions

Drug Interactions

This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.

Not Available

Food Interactions

• Take after a meal. Alcloxa is an ingredient used in toothpaste and brushing teeth after each meal is recommended.

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Active Moieties

Name	Kind	UNII	CAS	InChI Key
Allantoin	unknown	344S277G0Z	97-59-6	POJWUDADGALRAB-UHFFFAOYSA-N

Over the Counter Products

Name	Dosage	Strength	Route	Labeller	Marketing Start	Marketing End	Region	Image
Exoden Cure Powder	Powder	0.16 g/100g	Topical	Lifeon Corp.	2021-03-09	Not applicable

Mixture Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End	Region	Image
28tak Gum Care Tooth	Alcloxa (0.12 g/120g) + Aminocaproic acid (0.12 g/120g) + Calcium phosphate, dibasic (0.12 g/120g) + Calcium carbonate (36.0 g/120g)	Paste, dentifrice	Oral	Elmeditec Co.,Ltd	2018-07-01	Not applicable
Clean Breath Tooth	Alcloxa (0.06 g/100g) + Aminocaproic acid (0.06 g/100g) + Calcium phosphate, dibasic (0.07 g/100g) + Calcium carbonate (36 g/100g)	Paste, dentifrice	Dental	K.Boeun Pharmaceutical Co.,Ltd.	2021-01-01	Not applicable
Clean Breath Tooth	Alcloxa (0.06 g/100g) + Aminocaproic acid (0.06 g/100g) + Calcium phosphate, dibasic (0.07 g/100g) + Calcium carbonate (36 g/100g)	Paste, dentifrice	Dental	K.Boeun Pharmaceutical Co.,Ltd.	2021-11-30	Not applicable
Clean Breath Tooth	Alcloxa (0.06 g/100g) + Aminocaproic acid (0.06 g/100g) + Calcium phosphate, dibasic (0.07 g/100g) + Calcium carbonate (36 g/100g)	Paste, dentifrice	Dental	K.Boeun Pharmaceutical Co.,Ltd.	2021-05-01	Not applicable
Divinetree Ssak Shark Kids Tooth	Alcloxa (0.08 g/50g) + Silicon dioxide (6.50 g/50g)	Paste, dentifrice	Oral	K.biocos	2019-11-01	Not applicable

Unapproved/Other Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End	Region	Image
28tak Gum Care Tooth	Alcloxa (0.12 g/120g) + Aminocaproic acid (0.12 g/120g) + Calcium phosphate, dibasic (0.12 g/120g) + Calcium carbonate (36.0 g/120g)	Paste, dentifrice	Oral	Elmeditec Co.,Ltd	2018-07-01	Not applicable
Clean Breath Tooth	Alcloxa (0.06 g/100g) + Aminocaproic acid (0.06 g/100g) + Calcium phosphate, dibasic (0.07 g/100g) + Calcium carbonate (36 g/100g)	Paste, dentifrice	Dental	K.Boeun Pharmaceutical Co.,Ltd.	2021-11-30	Not applicable
Clean Breath Tooth	Alcloxa (0.06 g/100g) + Aminocaproic acid (0.06 g/100g) + Calcium phosphate, dibasic (0.07 g/100g) + Calcium carbonate (36 g/100g)	Paste, dentifrice	Dental	K.Boeun Pharmaceutical Co.,Ltd.	2021-01-01	Not applicable
Clean Breath Tooth	Alcloxa (0.06 g/100g) + Aminocaproic acid (0.06 g/100g) + Calcium phosphate, dibasic (0.07 g/100g) + Calcium carbonate (36 g/100g)	Paste, dentifrice	Dental	K.Boeun Pharmaceutical Co.,Ltd.	2021-05-01	Not applicable
Divinetree Ssak Shark Kids Tooth	Alcloxa (0.08 g/50g) + Silicon dioxide (6.50 g/50g)	Paste, dentifrice	Oral	K.biocos	2019-11-01	Not applicable

Categories

Drug Categories

Not Available

Classification

Not classified

Affected organisms

Not Available

Chemical Identifiers

UNII

18B8O9DQA2

CAS number

1317-25-5

InChI Key

IMZDRXBSGZPLDE-UHFFFAOYSA-H

InChI

InChI=1S/C4H6N4O3.2Al.ClH.4H2O/c5-3(10)6-1-2(9)8-4(11)7-1;;;;;;;/h1H,(H5,5,6,7,8,9,10,11);;;1H;4*1H2/q;2*+3;;;;;/p-6

IUPAC Name

dialuminium(3+) 4-(carbamoylamino)-2,5-dioxoimidazolidin-1-ide chloride tetrahydroxide

SMILES

[OH-].[OH-].[OH-].[OH-].[Al+3].[Al+3].[Cl-].NC(=O)NC1NC(=O)[N-]C1=O

References

General References

Not Available

External Links

ChemSpider

32698939

RxNav

1305554

Wikipedia

Alcloxa

Clinical Trials

Clinical Trials

Phase	Status	Purpose	Conditions	Count

Pharmacoeconomics

Manufacturers

Not Available

Packagers

Not Available

Dosage Forms

Form	Route	Strength
Paste, dentifrice	Oral
Paste	Topical
Powder	Topical	0.16 g/100g
Paste	Oral
Paste, dentifrice	Topical
Cream	Topical
Gel, dentifrice	Oral
Paste, dentifrice	Dental
Liquid	Topical

Prices

Not Available

Patents

Not Available

Properties

State

Not Available

Experimental Properties

Not Available

Predicted Properties

Property	Value	Source
Water Solubility	2.35 mg/mL	ALOGPS
logP	-1.4	ALOGPS
logP	-2.4	Chemaxon
logS	-2	ALOGPS
pKa (Strongest Acidic)	7.95	Chemaxon
pKa (Strongest Basic)	-3.4	Chemaxon
Physiological Charge	0	Chemaxon
Hydrogen Acceptor Count	4	Chemaxon
Hydrogen Donor Count	3	Chemaxon
Polar Surface Area	110.52 Å2	Chemaxon
Rotatable Bond Count	1	Chemaxon
Refractivity	31.22 m3·mol-1	Chemaxon
Polarizability	12.54 Å3	Chemaxon
Number of Rings	1	Chemaxon
Bioavailability	1	Chemaxon
Rule of Five	Yes	Chemaxon
Ghose Filter	No	Chemaxon
Veber's Rule	No	Chemaxon
MDDR-like Rule	No	Chemaxon

Predicted ADMET Features

Not Available

Spectra

Mass Spec (NIST)

Not Available

Spectra

Not Available

Chromatographic Properties

Collision Cross Sections (CCS)

Not Available

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Drug created at December 03, 2015 16:51 / Updated at September 28, 2021 21:54