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Ulixertinib
go.drugbank.com/drugs/DB13930InvestigationalIt is currently in clinical trials for the treatment of a wide range of tumors. … Ulixertinib is a a novel, reversible, ATP-competitive ERK1/2 inhibitor with high potency and ERK1/2 selectivity [A31474].
Thiostrepton
go.drugbank.com/drugs/DB11467InvestigationalVet approvedThiostrepton is a natural product of the ribosomally synthesized and post-translationally modified peptide class. … Thiostrepton is a natural cyclic oligopeptide antibiotic, derived from several strains of streptomycetes including Streptomyces azureus and Streptomyces laurentii.
Iferanserin
go.drugbank.com/drugs/DB11686InvestigationalIferanserin has been investigated for the treatment of Hemorrhoids.
Artefenomel
go.drugbank.com/drugs/DB11809InvestigationalArtefenomel has been investigated for the treatment of Malaria.
Lupeol
go.drugbank.com/drugs/DB12622InvestigationalLupeol has been investigated for the treatment of Acne.
Veldoreotide
go.drugbank.com/drugs/DB12777InvestigationalSomatoprim is under investigation for the treatment of Acromegaly.
ECT-001 expanded cord blood
go.drugbank.com/drugs/DB21745Investigational[L52013] It is being investigated in hematopoietic cell transplantation as ECT-001 expanded cord blood can demonstrate enhanced stem cell proliferation and engraftment compared to untreated UBCs.
R-851
go.drugbank.com/drugs/DB05747ExperimentalR-851 is part of the family of immune response modifier (IRM) and it acts in a novel way to stimulate the human body's immnune system to attack virus-infected cells and tumor cells. … It is expected to be topical treatment for cervical displasia and cervical high-risk human papillomavirus (HPV), the sexually transmitted virus that causes most cases of cervical cancer.
N,N-dimethylarginine
go.drugbank.com/drugs/DB01686ExperimentalIt is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells which is closely related to L-arginine, a conditionally-essential amino acid. … ADMA interferes with L-arginine in the production of nitric oxide, a key chemical to endothelial and hence cardiovascular health.
Totrombopag
go.drugbank.com/drugs/DB05930InvestigationalSB-559448 is a small-molecule drug that mimics the activity of thrombopoietin (TPO), a protein factor that promotes growth and production of blood platelets. … , thus representing a significant problem in the treatment of cancer patients.