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Navafenterol
go.drugbank.com/drugs/DB19195InvestigationalNavafenterol is under investigation in clinical trial NCT02971293 (Efficacy, Pharmacokinetics (PK), Safety and Tolerability Study of Inhaled AZD8871).
Cannabidiolic acid
go.drugbank.com/drugs/DB19261InvestigationalCannabidiolic acid is under investigation in clinical trial NCT04103814 (Effect of Topical CBD Cream for Degenerative Hallux Disorders).
Chimeric antigen receptor T-cells
go.drugbank.com/drugs/DB22146InvestigationalChimeric Antigen Receptor T-cells is under investigation in clinical trial NCT05225363 (Modified Immune Cells (TAG72-CAR T Cells) for the Treatment of Patients With Platinum Resistant Epithelial Ovarian
GLPG-1205
go.drugbank.com/drugs/DB15346InvestigationalGLPG-1205 is under investigation in clinical trial NCT03725852 (A Clinical Study to Test How Effective and Safe GLPG1205 is for Patients With Idiopathic Pulmonary Fibrosis (IPF)).
ALT-P1
go.drugbank.com/drugs/DB18485InvestigationalALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. It is under investigation for the treatment of growth hormone deficiency.
RD13-02
go.drugbank.com/drugs/DB27110InvestigationalRD13-02 is a biologic drug. RD13-02 is under investigation in clinical trial NCT05923541 (RD13-02 for Patients With r/r CD7+ T Cell Hematologic Malignancies).
Ginsenoside Rg1
go.drugbank.com/drugs/DB06750ExperimentalNutraceuticalRg1 Appears to be most abundant in Panax ginseng (Chinese/Korean Ginseng). It improves spatial learning and increase hippocampal synaptophysin level in mice, plus demonstrates estrogen-like activity. … Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng).
AVR-RD-05
go.drugbank.com/drugs/DB18631ExperimentalIt is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII). … AVR-RD-05 is a gene therapy comprising genetically modified autologous stem cells transduced _ex vivo_ with a lentiviral vector encoding the human iduronate-2-sulfatase (IDS) enzyme.
Anti-SARS-CoV-2 IgY
go.drugbank.com/drugs/DB16356Investigational[L27381] To create these antibodies, chickens are injected in the chest with the spike protein, which is the surface protein of SARS-CoV-2; this results in an immune response mounted by the chickens towards … These antibodies are currently being investigated against COVID-19 in the trial NCT04567810 (Safety, Tolerability, and Pharmacokinetics of Anti-Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV
BBIBP-CorV
go.drugbank.com/drugs/DB15807InvestigationalAs of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials. … Investigation shows this vaccine induces neutralizing antibodies in several mammalian species while also showing protective efficacy with SARS-CoV-2 challenge in rhesus macaques[A219763].