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EXT608
go.drugbank.com/drugs/DB18453InvestigationalEXT608 is a long-acting PTH derivative under investigation for the treatment of hyperparathyroidism.[L48270]
Ispectamab debotansine
go.drugbank.com/drugs/DB18456InvestigationalIspectamab debotansine is an antibody drug conjugate comprised of an anti-B cell maturation (BCMA) IgG1 humanized antibody conjugated covalently to the dibenzocyclooctyne (DBCO) noncleavable linker maytansinoid
Zilovertamab vedotin
go.drugbank.com/drugs/DB18457Investigationalmc-vc-PAB), and a monomethyl auristatin E (MMAE) cytotoxin. … Zilovertamab vedotin is an Antibody-drug conjugate (ADC) comprising an anti-ROR1 monoclonal antibody (UC-961), a proteolytically cleavable maleimidocaproyl-valine-citrulline-para-aminobenzoate linker (
Rodatristat ethyl
go.drugbank.com/drugs/DB18479InvestigationalSynonyms: 2,8-diazaspiro(4.5)decane-3-carboxylic acid, 8-(2-amino-6-((1r)-1-(5-chloro(1,1'-biphenyl)-2-yl)-2,2,2-trifluoroethoxy)-4-pyrimidinyl)-, ethyl ester, (3s)-, Ethyl (3s)-8-(2-amino-6-((1r)-1-(5-chloro(1,1'-biphenyl)-2-yl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)-2,8-diazaspiro(4.5)decane-3-carboxylateCategories: Heterocyclic Compounds, 1-RingEI-1071
go.drugbank.com/drugs/DB18486InvestigationalEI-1071 is a selective Colony Stimulating Factor-1 Receptor kinase inhibitor.
GTB-3550
go.drugbank.com/drugs/DB18494InvestigationalGTB-3550 is a single-chain, tri-specific scFv recombinant fusion protein conjugate composed of the variable regions of the heavy and light chains of anti-CD16 and anti-CD33 antibodies and a modified form
Synonyms: single chain recombinant trispecific killer engager consistent of anti-CD16 scFV spliced to anti-CD33 scFV with a modified IL-15 linkerAPR-2020
go.drugbank.com/drugs/DB18497InvestigationalAPR-2020 is a CD34+ cells that have been transduced in vitro with a lentiviral vector carrying a codon-optimized sequence for expressing the wild type RPS19 protein
TRK-250
go.drugbank.com/drugs/DB18500InvestigationalTRK-250 is a small interfering RNA agent that targets human transforming growth factor-beta 1 (TGF-β1) messenger RNA.
RAG-17
go.drugbank.com/drugs/DB18503InvestigationalRAG-17 is a siRNA oligonucleotide designed to target and knockdown the expression of superoxide dismutase (SOD).