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VIR-5818
go.drugbank.com/drugs/DB28582InvestigationalVIR-5818 is a biologic drug. … VIR-5818 is under investigation in clinical trial NCT05356741 (To Access the Safety and Effects of Intravenous Administration of VIR-5818 Alone and in Combination With Pembrolizumab in Adult Participants
Adermastat
go.drugbank.com/drugs/DB28906InvestigationalAdermastat is a small molecule drug. … Adermastat is under investigation in clinical trial NCT03858686 (The Effect of FP-025, on Allergen-induced Airway Responses in Mild Eosinophilic House Dust Mite (HDM)-Allergic Asthma.).
Acellular nerve allograft
go.drugbank.com/drugs/DB30293ApprovedInvestigationalApproved by the FDA under a Biologics License Application (BLA) as an acellular nerve scaffold for the treatment of adult and pediatric patients (aged ≥1 month) with sensory, mixed, and motor peripheral … Our team is working on the full update, which will be available soon. [L54673,L54668]
MVR-C5252
go.drugbank.com/drugs/DB30379InvestigationalMVR-C5252 is a biologic drug. MVR-C5252 is under investigation in clinical trial NCT06126744 (Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of the Oncolytic HSV1 MVR-C5252).
FRAX716
go.drugbank.com/drugs/DB31795ExperimentalFRAX716 is a group I-specific p21-activated kinase (PAK) inhibitor which dramatically inhibits the phosphorylation of PAK and Mek1.[A274678]
PHB-050
go.drugbank.com/drugs/DB32061ExperimentalPHB-050 is a novel, next-generation anti-IgE antibody designed to block IgE from binding to mast cells, while also rapidly reducing circulating IgE and inhibiting its production. … [L54988] It is under investigation for the treatment of multiple atopic diseases, including food allergies, asthma, and atopic dermatitis.[L54988]
Zamubafusp alfa
go.drugbank.com/drugs/DB32269InvestigationalZamubafusp alfa is an immunoglobulin-peptide fusion protein.[L55038] It consists of a humanized IgG1 and p5R which is a pan-amyloid reactive peptide.[L55038]
YMI024
go.drugbank.com/drugs/DB32602ExperimentalYMI024 is a drug being investigated for inflammation-driven diseases.[L56081]
SI-109
go.drugbank.com/drugs/DB32603ExperimentalSI-109 is a potent, small-molecule inhibitor of the STAT3 SH2 domain.[A275443]
GLB-001
go.drugbank.com/drugs/DB32795InvestigationalGLB-001 is a orally bioavailable molecular glue degrader targeting casein kinase 1 alpha (CK1a).[L56124, L56125, L56126]