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Displaying results 981 - 990 of 10000 in total
  1. Drug

    4-[(5-CHLOROINDOL-2-YL)SULFONYL]-2-(2-METHYLPROPYL)-1-[[5-(PYRIDIN-4-YL)PYRIMIDIN-2-YL]CARBONYL]PIPERAZINE

    go.drugbank.com/drugs/DB04673
    Experimental

    Synonyms: 4-[(5-CHLOROINDOL-2-YL)SULFONYL]-2-(2-METHYLPROPYL)-1-[[5-(PYRIDIN-4-YL)PYRIMIDIN-2-YL]CARBONYL]PIPERAZINE
  2. Drug

    Muscimol

    go.drugbank.com/drugs/DB12458
    Investigational

    Muscimol has been used in trials studying the treatment of Epilepsy and Parkinson's Disease.

    Synonyms: 5-(aminomethyl)-3(2H)-isoxazoloneCategories: GABA-A Receptor Agonists, Heterocyclic Compounds, 1-Ring
  3. Drug

    Cabazitaxel

    go.drugbank.com/drugs/DB06772
    ApprovedInvestigational

    It was first approved by the FDA on June 17, 2010.[A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17, 2019.[L47376] … Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic IndexSynonyms: 1-HYDROXY-7.BETA.,10.BETA.-DIMETHOXY-9-OXO-5.BETA.,20-EPOXYTAX-11-ENE-2.ALPHA.,4,13.ALPHA.-TRIYL 4-ACETATE 2-BENZOATE 13-((2R,3S)-3-(((TERT-BUTOXY)CARBONYL)AMINO)-2-HYDROXY-3-PHENYLPROPANOATE)
  4. Drug

    Light mineral oil

    go.drugbank.com/drugs/DB11579
    Approved

    Synonyms: Drakeol 5Mixtures: retaine MGD
  5. Drug

    Brosotamide

    go.drugbank.com/drugs/DB19926
    Experimental

    Brosotamide is a small molecule drug. Brosotamide has a monoisotopic molecular weight of 228.97 Da.

    Synonyms: 5-bromo-2,3-cresotamide
  6. Drug

    Enpatoran

    go.drugbank.com/drugs/DB16501
    Investigational

    It was investigated for systemic lupus erythematosus and cutaneous lupus erythematosus in completed trials (NCT04647708 and NCT05162586) and in a recruiting trial (NCT05540327). … Additionally, M5049 was studied for COVID-19 pneumonia in a completed trial with results (NCT04448756) and is currently being recruited for a trial involving participants with dermatomyositis and polymyositis

    Synonyms: 5-((3R,5S)-3-AMINO-5-TRIFLUOROMETHYLPIPERIDIN-1-YL)QUINOLINE-8-CARBONITRILE
  7. Drug

    Bicyclol

    go.drugbank.com/drugs/DB16014
    Investigational

    Bicyclol is under investigation in clinical trial NCT02944552 (The Multi Center, Randomized, Double-blind, Positive Controlled Study of Bicyclol in the Treatment of Acute DILI).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 4,4'-bi-1,3-benzodioxole)-5-carboxylic acid, 5'-(hydroxymethyl)-7,7'-dimethoxy-, methyl ester
  8. Drug

    25-Hydroxycholesterol

    go.drugbank.com/drugs/DB04705
    Experimental

    Synonyms: Cholest-5-ene-3beta,25-diol, 5-Cholestene-3beta,25-diol
  9. Drug

    NIP-292

    go.drugbank.com/drugs/DB18055
    Investigational

    Synonyms: 4-fluoro-5-((6-methylhexahydropyrrolo[3,4-b] pyrrol-5(1H)-yl) sulfonyl) isoquinoline
  10. Drug

    Nortriptyline

    go.drugbank.com/drugs/DB00540
    ApprovedInvestigational

    Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant (TCA). … [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.[L11881]

    Categories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT2 Receptor AntagonistsSynonyms: 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine, 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine