Bicyclol

DB16014InvestigationalSmall molecule

Bicyclol is under investigation in clinical trial NCT02944552 (The Multi Center, Randomized, Double-blind, Positive Controlled Study of Bicyclol in the Treatment of Acute DILI).

Mechanism: Pharmacologically active on Heat shock factor protein 1
Curator reviewed
Formula / weight: C₁₉H₁₈O₉ · 390.344 g/mol (avg)
Also known as: 4,4'-bi-1,3-benzodioxole)-5-carboxylic acid, 5'-(hydroxymethyl)-7,7'-dimethoxy-, methyl ester
Code names: SY 801

Resolves to

Compound

UNII9734122TH2CAS118159-48-1ChEMBLCHEMBL482035

Structure

InChIKeyKXMTXZACPVCDMH-UHFFFAOYSA-NSMILESCOC(=O)C1=C(C2=C(OCO2)C(OC)=C1)C1=C(CO)C=C(OC)C2=C1OCO2

Targets

Q00613HSF1

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

4Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Bicyclol, and which of those have an active Phase 3 trial?

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