Search
Ilacirnon
go.drugbank.com/drugs/DB16066InvestigationalIlacirnon (CCX-140) is under investigation in clinical trial NCT01440257 (A Study to Evaluate the Effect of CCX140-B on Urinary Albumin Excretion in Subjects With Type 2 Diabetes and Albuminuria).
Synonyms: 4-Chloro-N-[5-methyl-2-(7H-pyrrolo[2,3-d]pyrimidin-4-ylcarbonyl)-3-pyridinyl]-3-(trifluoromethyl)benzenesulfonamideIndoramin
go.drugbank.com/drugs/DB08950ApprovedWithdrawnIt is a selective alpha-1 adrenergic antagonist with no reflex tachycardia and direct myocardial depression action. … Indoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese.
Devafidugene civaparvovec
go.drugbank.com/drugs/DB16790InvestigationalIt uses proprietary zinc finger nucleases (ZFN) that insert a functional copy of the alpha-L-iduronidase (IDUA) enzyme. … Developed by Sangamo Therapeutics, Inc., devafidugene civaparvovec is being investigated for the treatment of mucopolysaccharidosis Type I (MPS I).[L46716]
Carbon black
go.drugbank.com/drugs/DB11980Investigational[A263401] Upon inhalation, carbon black has been reported to trigger an inflammatory response in the lung tissue [A263401] and has been linked to carcinogenicity.[A263406, A263411, A263416] … Produced by the incomplete combustion of hydrocarbons, carbon black is an insoluble pigment [A263396] with demonstrated adverse effects on pulmonary function.
Synonyms: D&C BLACK NO. 2 [II], DC BLACK NO. 2N,N-dimethylarginine
go.drugbank.com/drugs/DB01686ExperimentalIt is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells which is closely related to L-arginine, a conditionally-essential amino acid. … Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma.
Synonyms: N(5)-((Dimethylamino)iminomethyl)-L-ornithine, dimethyl-L-arginineGSK2245035
go.drugbank.com/drugs/DB16076InvestigationalGSK2245035 is under investigation in clinical trial NCT02833974 (Effect of the GSK2245035 on the Allergen-induced Asthmatic Response).
Stapokibart
go.drugbank.com/drugs/DB18990InvestigationalStapokibart is under investigation in clinical trial NCT06424470 (Study on the Treatment of Prurigo Nodularis With Stapokibart Injection).
norUrsodeoxycholic acid
go.drugbank.com/drugs/DB16260InvestigationalnorUrsodeoxycholic acid is under investigation in clinical trial NCT03872921 (Norursodeoxycholic Acid vs Placebo in PSC).
Poseltinib
go.drugbank.com/drugs/DB16299InvestigationalPoseltinib is under investigation in clinical trial NCT02628028 (A Study of LY3337641 in Rheumatoid Arthritis).
Sodelglitazar
go.drugbank.com/drugs/DB16332InvestigationalSodelglitazar is under investigation in clinical trial NCT00196989 (Study in People With Type 2 Diabetes).