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Displaying results 9941 - 9950 of 10000 in total
  1. Drug

    PX-12

    go.drugbank.com/drugs/DB05448
    Investigational

    PX-12 (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), stimulates apoptosis, down-regulates HIF-1α and vascular endothelial growth factor (VEGF) and inhibits … Since high levels of Trx-1 have been associated with colorectal, gastric and lung cancers, PX-12 is indicated as a potential cancer treatment in combination with chemotherapy for patients with advanced

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-Methylpropyl-2-imidazolyl disulfide
  2. Drug

    Dociparstat sodium

    go.drugbank.com/drugs/DB16481
    Investigational

    Synonyms: 2,3-o-Desulfated heparin (12000 da)
  3. Drug

    Elvucitabine

    go.drugbank.com/drugs/DB06236
    Investigational

    Synonyms: B-L-Fd4CCategories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Saredutant

    go.drugbank.com/drugs/DB06660
    Investigational

    Saredutant (SR 48968) is a neurokinin-2 antagonist drug being developed as an antidepressant and anxiolytic by Sanofi-Aventis.

    Categories: Heterocyclic Compounds, 1-Ring, Receptors, Neurokinin-2, antagonists & inhibitors
  5. Drug

    Enpatoran

    go.drugbank.com/drugs/DB16501
    Investigational

    Additionally, M5049 was studied for COVID-19 pneumonia in a completed trial with results (NCT04448756) and is currently being recruited for a trial involving participants with dermatomyositis and polymyositis … It was investigated for systemic lupus erythematosus and cutaneous lupus erythematosus in completed trials (NCT04647708 and NCT05162586) and in a recruiting trial (NCT05540327).

    Synonyms: 5-((3R,5S)-3-AMINO-5-TRIFLUOROMETHYLPIPERIDIN-1-YL)QUINOLINE-8-CARBONITRILE
  6. Drug

    TJ003234

    go.drugbank.com/drugs/DB16470
    Investigational

  7. Drug

    Istaroxime

    go.drugbank.com/drugs/DB06157
    Investigational

    Synonyms: (E,Z)-Istaroxime, 3-((2-Aminoethoxy)imino)-5alpha-androstan-6,17-dione
  8. Drug

    Lexatumumab

    go.drugbank.com/drugs/DB06599
    Investigational

    Lexatumumab is a fully humanized, high-affinity immunoglobulin G(1 lambda) monoclonal antibody (mAb).

  9. Drug

    MAS825

    go.drugbank.com/drugs/DB16452
    Investigational

  10. Drug

    HMR4011

    go.drugbank.com/drugs/DB06225
    Experimental

    HMR4011 (IPL 576,092) is a novel steroidal anti-inflammatory compound with a mechanism of action distinct from that of glucocorticoid. … IPL 576,092 has previously been investigated as a treatment for asthma.