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RUTI® Vaccine
go.drugbank.com/drugs/DB15853InvestigationalSponsored by Fundació Institut Germans Trias i Pujol, the RUTI® Vaccine is being tested for prevention of COVID-19 infection in a controlled trial with 315 healthcare worker participants (NCT04453488). … Much like the BCG vaccine, the RUTI® vaccine is also being tested as a prophylactic for SARS-CoV2.
BBM-H803
go.drugbank.com/drugs/DB17700InvestigationalIt consists of an adeno-associated virus vector containing an expression cassette of the human Factor VIII transgene. … BBM-H803 is a recombinant adeno-associated virus (AAV) based gene therapy drug for hemophilia A developed and manufactured by Belief BioMed.
Uprifosbuvir
go.drugbank.com/drugs/DB15206InvestigationalUprifosbuvir is under investigation in clinical trial NCT02332707 (Efficacy and Safety of Grazoprevir (MK-5172) and Uprifosbuvir (MK-3682) With Elbasvir (MK-8742) or Ruzasvir (MK-8408) for Chronic Hepatitis
Allocetra
go.drugbank.com/drugs/DB16424Investigationalso that the immune system is rebalanced back to normal -- averting a cytokine storm. … Allocetra is a novel therapy where billions of early apoptotic cells are infused into the bloodstream of a patient, using the body's own natural regulation mechanisms to rebalance an unbalanced immune
Bithionol
go.drugbank.com/drugs/DB04813ApprovedWithdrawnBithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders.
International brands: Vancide BLMedical Cannabis
go.drugbank.com/drugs/DB14009InvestigationalWhile cannabis in its natural plant form is currently used "off-label" for the management of many medical conditions, THC is currently commercially available in synthetic form as [DB00486], as purified … In contrast, CB2 receptors are mainly found peripherally in immune cells, lymphoid tissue, and peripheral nerve terminals [A32676].
XAV-19
go.drugbank.com/drugs/DB15895InvestigationalXAV-19 is an intravenous antibody-based treatment targeted towards SARS-CoV-2 and other coronaviruses[L16553,L16558]. The therapy concept is based on [COVID-19 convalescent plasma]. … As of July, 2020, the company is conducting a Phase 2 randomized clinical trial to define dosing safety and efficacy of XAV-19 (NCT04453384).
N-(carboxycarbonyl)-D-phenylalanine
go.drugbank.com/drugs/DB08263ExperimentalIt targets the protein hypoxia-inducible factor 1-alpha inhibitor. … N-(carboxycarbonyl)-D-phenylalanine is a solid. This compound belongs to the n-acyl-alpha amino acids.
6-ethyl-5-[(2S)-1-(3-methoxypropyl)-2-phenyl-1,2,3,4-tetrahydroquinolin-7-yl]pyrimidine-2,4-diamine
go.drugbank.com/drugs/DB08099Experimental6-ethyl-5-[(2s)-1-(3-methoxypropyl)-2-phenyl-1,2,3,4-tetrahydroquinolin-7-yl]pyrimidine-2,4-diamine is a solid. This compound belongs to the phenylquinolines.
Synonyms: 6-ethyl-5-[(2S)-1-(3-methoxypropyl)-2-phenyl-1,2,3,4-tetrahydroquinolin-7-yl]pyrimidine-2,4-diamineDihydroxymethoxychalcone
go.drugbank.com/drugs/DB14122InvestigationalCardamonin's name comes from the fact that it can be found in cardamom spice.