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Antihemophilic factor human

go.drugbank.com/drugs/DB13192
ApprovedInvestigational

Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential component of the coagulation cascade. Antihemophilic factor is manufactured with reduced amounts of von Wil...

  1. Drug

    Antihemophilic factor, human recombinant

    go.drugbank.com/drugs/DB00025
    ApprovedInvestigational

    Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells

    Categories: Human Antihemophilic Factors, Biological FactorsSynonyms: Antihemophilic factor, human recombinant, Human factor VIII recombinant
  2. Drug

    Antihemophilic factor (recombinant), PEGylated

    go.drugbank.com/drugs/DB09329
    ApprovedInvestigational

    Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated … Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product _Adynovate_ [FDA label].

    Categories: Human Antihemophilic Factors, Biological FactorsSynonyms: Antihemophilic Factor (Recombinant), PEGylated, antihemophilic factor (recombinant), PEGylated-aucl
  3. Drug

    Coagulation Factor IX Human

    go.drugbank.com/drugs/DB13152
    ApprovedInvestigational

    Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes hemophilia B.

    Synonyms: Antihemophilic factor B, Factor IX (Human)Mixtures: UMAN COMPLEX, UMAN COMPLEX
  4. Drug

    Von Willebrand factor human

    go.drugbank.com/drugs/DB13133
    ApprovedInvestigational

    [L40049] As vWF is normally present in the blood as a stable complex with coagulation factor III, therapeutic vWF products are also available as a combination product with [antihemophilic factor human] … The human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis.

    Mixtures: von Willebrand Factor/Coagulation Factor VIII Complex (Human), Wilate - von Willebrand Factor/Coagulation Factor VIII Complex (Human)Categories: Biological Factors, von Willebrand factor and coagulation factor VIII in combination
  5. Drug

    Factor IX Complex (Human)

    go.drugbank.com/drugs/DB11330
    ApprovedInvestigational

    of Factor VII (proconvertin) derived from human plasma. … Also known as prothrombin complex concentrate, products containing this complex often include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and low levels

    Categories: Factor IX, Biological FactorsSynonyms: Factor IX complex human, Factor IX complex,human
  6. Drug

    Rurioctocog alfa pegol

    go.drugbank.com/drugs/DB16007
    ApprovedInvestigational

    Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor. … [A245149] Hemophilia A is the most common inherited bleeding disorder leading to deficiency of factor VIII, which is caused by defects in the F8C gene that encodes coagulation factor VIII.

    Categories: Factor VIII, Biological FactorsSynonyms: Antihemophilic factor, pegylated (mw 20000) human sequence recombinant, Antihemophilic factor (recombinant), pegylated (20 kda)
  7. Drug

    Moroctocog alfa

    go.drugbank.com/drugs/DB13999
    Approved

    is a fully recombinant factor VIII-Fc fusion protein which has an extended half-life compared with conventional factor VIII due to conjugation to the dimeric Fc domain of human immunoglobulin G1, a long-lived … VIII, the essential human blood clotting protein that is impaired in Hemophilia A.

    Categories: Biological Factors, Blood Coagulation FactorsSynonyms: Antihemphilic factor, recombinant human B-domain deleted, Human factor VIII, recombinant B-domain deleted
  8. Drug

    Efmoroctocog alfa

    go.drugbank.com/drugs/DB11607
    ApprovedInvestigational

    VIII, but does not contain the B-domain, which has no known biological function, and [DB13192], which is purified endogenous Factor VIII from human pooled blood and contains both A- and B-subunits. … Factor VIII is a blood coagulant factor involved in the intrinsic pathway to form fibrin, or a blood clot.

    Categories: Human Antihemophilic FactorsSynonyms: Antihemophilic factor (recombinant, FC fusion protein), Antihemophilic Factor (Recombinant BDD), FC Fusion Protein
  9. Drug

    Susoctocog alfa

    go.drugbank.com/drugs/DB11606
    ApprovedInvestigational

    The recombinant porcine sequence allows less susceptibility to inactivation by circulating human factor VIII antibodies. … These autoantibodies neutralize circulating human factor VIII and create a functional deficiency of this procoagulant protein.

    Categories: Blood Coagulation FactorsSynonyms: Antihemophilic factor (recombinant) porcine sequence, ANTIHEMOPHILIC FACTOR (RECOMBINANT), PORCINE SEQUENCE