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  1. Pathway

    Antihemophilic Factor Human Action Pathway

    smpdb.ca/view/SMP0126841
    Drug action

    Antihemophilic factor human, also known as Hemofil, Koate, and Wilate is used as factor VIII replacement therapy to treat hemophilia A. … Administered intravenously the antihemophilic factor human replaces the abnormal coagulation factor VIII, acting as a cofactor to activate coagulation factor IX and X.

    Drugs: Calcium · Antihemophilic factor human
    Enzymes: Tissue factor, Coagulation factor VIII
  2. Pathway

    Antihemophilic Factor Human Recombinant Action Pathway

    smpdb.ca/view/SMP0126774
    Drug action

    Antihemophilic factor, human recombinant is administered intravenously and acts to correct coagulation defects, by activating coagulation factor X and IX. … Antihemophilic factor, human recombinant of the coagulation Factor VIII, also known as Advate, Adynovate, Helixate, Kogenate, Kovaltry, Novoeight, Recombinate, to treat hemophilia A, von Willebrand disease

    Drugs: Antihemophilic factor, human recombinant · Calcium
    Enzymes: Tissue factor, Coagulation factor VIII
  3. Pathway

    Moroctocog Alfa Action Pathway

    smpdb.ca/view/SMP0126849
    Drug action

    Moroctocog alfa also known as Refacto AF and Xyntha, is a B-domain deleted recombinant factor VIII similar to the endogenous coagulation factor VIII. … It acts by replacing coagulation factor VIII which is deficient in those with hemophilia, this allows coagulation factor IX and X to be activated and facilitate the clotting cascade.

    Drugs: Calcium · Moroctocog alfa
    Enzymes: Tissue factor, Coagulation factor VIII