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Antithrombin-III

AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa (PubMed:15140129). Its inhibitory activity is greatly enhanced in the presence of heparin

Human Cyclooxygenases

Similarly catalyzes successive cyclooxygenation and peroxidation of dihomo-gamma-linoleate (DGLA, C20:3(n-6)) and eicosapentaenoate (EPA, C20:5(n-3)) to PGH1 and PGH3, the precursors of 1- and 3-series … and 18S-RvE2 (PubMed:21206090).

Human Carboxylesterases

Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs (PubMed:9169443). … Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes of 2-arachidonoylglycerol and prostaglandins (PubMed:21049984)

Human Isocitrate Dehydrogenases

The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity … The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity

Human vesicular glutamate transporters

Human telomerase RNA component

Human Arylsulfatase A mRNA

Plasmepsin III

Digestion of host Hb is an essential step which provides the parasite with amino acids for protein synthesis, and regulates osmolarity (Probable).

HERG human cardiac K+ channel

Channel properties are modulated by cAMP and subunit assembly (PubMed:10837251). … Exhibits faster activation and deactivation kinetics and slow inactivation at membrane potentials positive to 240 mV, resulting in the weakest inward rectification (PubMed:32723862)

Endonuclease III