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  1. Pathway

    Bivalirudin.

    smpdb.ca/view/SMP0000277
    Drug action

    As a result, bivalirudin prevents or reduces clot formation. … Bivalirudin does not need cofactor antithrobin to act. It binds circulating and clot-bound thrombin at the catalytic site and the anion binding exosite.

    Drugs: Bivalirudin · Phylloquinone · Calcium
    Enzymes: Bivalirudin
  2. Pathway

    Bivalirudin Action Pathway

    smpdb.ca/view/SMP0126441
    Drug action

    Bivalirudin is cleared from plasma by the renal system and proteolytic cleavage. … Bivalirudin is a direct thrombin inhibitor that treats heparin-induced thrombocytopenia and prevents thrombosis.

    Drugs: Bivalirudin · Calcium